Results 101 to 110 of about 2,033,218 (305)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Известия высших учебных заведений. Поволжский регион: Естественные наукиBackground. The study of the bird population structure will make it possible to determine the role of various landscapes in the formation of the biodiversity of the territory of the National Park “Sengileevskiye Gory” and lay the foundation for long-term
M.V. Korepov, P.O. Pavlov, S.V. Yakunin
doaj +1 more source
Fascism in Richmond: a brief history
, 2005 This article briefly explores the nature of local fascist activity in the Richmond-upon-Thames area during the 1920s and 1930s, such as the 'British Fascisti' and the 'British Union of Fascists'
Woodbridge, Steven
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A New Vision of Local History Narrative: Writing History in Cummington, Massachusetts
, 2009 Scholars who have written about local history hold no consensus on the purpose, value, and even definition of local history narrative. This thesis seeks to move the discussion away from territorial definitions of the term local history narrative and ...
Pasternak, Stephanie
core +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
The National Citizens Union in Richmond: a brief history
, 2006 This article briefly explores the nature and local activities of the National Citizens Union (formerly known as the Middle Classes Union) in the Richmond-upon-Thames area during the early 1920s. There has been very little written on the National Citizens
Woodbridge, Steven
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Defining memory : local museums and the construction of history in America's changing communities
, 2007 Defining Memory uses case studies of exhibits from around the country to examine how local museums, defined as museums whose collections are local in scope or whose audiences are primarily local, have both shaped and been shaped by evolving community ...
Levin, Amy K. 1957-
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