Results 31 to 40 of about 6,386,769 (253)

Asymptotic expansion of closed orbits in homology classes for Anosov flows. [PDF]

open access: yes, 2004
In this paper we give an asymptotic expansion including error terms for the number of closed orbits in the homology classes for homological full Anosov flows. In particular we obtain formulae concerning the coefficients of error terms which depend on the
Liu, Dongsheng
core   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

HoSeIn: A Workflow for Integrating Various Homology Search Results from Metagenomic and Metatranscriptomic Sequence Datasets

open access: yesBio-Protocol, 2020
Data generated by metagenomic and metatranscriptomic experiments is both enormous and inherently noisy. When using taxonomy-dependent alignment-based methods to classify and label reads, the first step consists in performing homology searches against ...
Gaston Rozadilla   +2 more
doaj   +1 more source

Searching remote homology with spectral clustering with symmetry in neighborhood cluster kernels. [PDF]

open access: yesPLoS ONE, 2013
Remote homology detection among proteins utilizing only the unlabelled sequences is a central problem in comparative genomics. The existing cluster kernel methods based on neighborhoods and profiles and the Markov clustering algorithms are currently the ...
Ujjwal Maulik, Anasua Sarkar
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Amino acid sequence homology between thyroid autoantigens and central nervous system proteins: Implications for the steroid-responsive encephalopathy associated with autoimmune thyroiditis

open access: yesJournal of Clinical & Translational Endocrinology, 2021
A few patients with Hashimoto’s thyroiditis or Graves’ disease develop a multiform syndrome of the central nervous system (CNS) termed Hashimoto’s encephalopathy or steroid-responsive encephalopathy associated with autoimmune thyroid disease (HE/SREAT ...
Salvatore Benvenga   +5 more
doaj   +1 more source

Integrative approaches to protein homology search [PDF]

open access: yes, 2005
Alam I. Integrative approaches to protein homology search. Bielefeld (Germany): Bielefeld University; 2005.Many methods have been developed to search for homologous members of a protein family in databases, and the reliability of results and conclusions ...
Alam, Intikhab
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

ON VANISHING OF GENERALIZED LOCAL HOMOLOGY MODULES AND ITS DUALITY [PDF]

open access: yesRomanian Journal of Mathematics and Computer Science, 2014
In this paper we study the vanishing and non-vanishing of generalized local cohomology and generalized local homology. In particular for a Noetherian local ring (R;m) and two non-zero finitely generated R-modules M and N, it is shown that H_m^{dimN} (M ...
KARIM MOSLEHI, MOHAMMAD R. AHMADI
doaj  

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