Results 61 to 70 of about 6,325,684 (293)
Motivations for local climate adaptation in Dutch municipalities: climate change impacts and the role of local-level government [PDF]
, 2009 The local government level is considered to be crucial in preparing society for climate change impact. Yet little is known about why local authorities do or do not take action to adapt their community for climate change impacts.
Berg, Maya M. van den
core +1 more source
Approximating Local Homology from Samples [PDF]
, 2013 Recently, multi-scale notions of local homology (a variant of persistent homology) have been used to study the local structure of spaces around a given point from a point cloud sample.
Skraba, Primoz, Wang, Bei
core +3 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Local Knowledge On Plants [PDF]
, 2016 The immense richness of the biodiversity of Malaysian flora has earned her a place as one of the twelve mega-biodiversity areas of the world. The local communities have long benefited from this biodiversity through various uses, as a result of their ...
Che Lah, Salasiah, Esa, Norizan
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
VertigO, 2005 There has been relatively little research in the social sciences on knowledge generated and exchanged by farmers in modern Western contexts. Yet organic farmers in Quebec are at the heart of an intense innovation that is re-creating local knowledge on ...
Mary Richardson
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Les savoirs locaux : entre connaissances et reconnaissance
VertigO, 2005 Local knowledge are more and more requested for interdisciplinary research or exercises of nature management. With the example of water management in France, we can study the place conferred to empirical knowledge held by amateur fishermen and the way in
Carole Barthélémy
doaj +1 more source
Citizen Science in Disaster and Conflict Resilience [PDF]
, 2010 *Background/Question/Methods* Within the disaster and conflict response communities, concern about lack of effectiveness of outside responses has led to a debate about the role of local people in developing the capacity to prepare for ...
Keith G Tidball, Marianne Krasny
core +2 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source