Results 71 to 80 of about 1,772,390 (303)
Scales of knowledge: North Sea fisheries governance, the local fisherman & the European scientist [PDF]
, 2009 Recent European Union fisheries governance reforms have included the development of new regional fora designed to enable stakeholders and scientists to deliberate together about the nature of the fisheries crisis and its possible solutions.
Griffin, L.
core +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Knowledge-Based Urban Development: The Local Economic Development Path of Brisbane, Australia [PDF]
, 2008 Knowledge-based development strategies play an important role in supporting local economic development of cities in the knowledge era. This paper investigates local knowledge-based urban development policies of Brisbane, Australia in its long journey to ...
Koray Velibeyoglu +3 more
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Traditional and local ecological knowledge about forest biodiversity in the Pacific Northwest / [PDF]
, 2008 This paper synthesizes the existing literature about traditional and local ecological knowledge relating to biodiversity in Pacific Northwest forests in order to assess what is needed to apply this knowledge to forest biodiversity conservation efforts ...
Jones, Eric T., 1965- +3 more
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Decentralization and Local Democracy in the World : First Global Report by United Cities and Local Governments 2008 [PDF]
, 2009 This overall picture of decentralization and local democracy in African countries shows significant progress at the strictly institutional level.
World Bank +1 more
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Exploring knowledge management integration through EAI in local government domain [PDF]
, 2010 Information Technology (IT) infrastructure integration and knowledge management share communal objectives e.g. to make organisations more effective and efficient, agile and innovative, and more responsive to market changes.
Kamal, M
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Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Web 2.0 and knowledge management for local government in England – A model for the public sector? [PDF]
, 2009 PURPOSE Delivering success in the public and private sector requires staff to have access to the best knowledge possible about how to do their jobs well so a major challenge for employers is how to ensure their staff are making decisions based on the ...
Leask, M
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