Results 61 to 70 of about 12,044,738 (293)

Using local scientific knowledge for transboundary conservation: distribution modelling for the taruka in South America

open access: yesOryx
Effective conservation management of threatened species with transboundary distributions is a challenge, requiring international coordination to ensure that country-specific actions align with regional imperatives. Many international conservation efforts
Nicolás Fuentes-Allende   +14 more
doaj   +1 more source

Validity of the Fisher Community Knowledge-Based Economic Valuation of the Local Ecosystem for Oyster Farming: A Case Study in Japan

open access: yesFrontiers in Marine Science, 2022
The importance of local knowledge as a relevant information resource for ecosystem conditions has recently been the focus of sustainable ecosystem management.
Junpei Shinji   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

De l’« efficacité » symbolique des interdits à leur fonctionnalité écologique

open access: yesRevue d'ethnoécologie, 2014
During the last few decades, environmental emergencies as well as mixed results of existing conservation systems, urges researchers and managers of protected areas to look up other forms of resource management models in non-Western cultures.
Hélène Artaud
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Elevating local knowledge through participatory modeling: active community engagement in restoration planning in coastal Louisiana

open access: yesJournal of Geographical Systems, 2019
Numerical modeling efforts in support of restoration and protection activities in coastal Louisiana have traditionally been conducted externally to any stakeholder engagement processes.
S. Hemmerling   +7 more
semanticscholar   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Local Knowledge and Conservation Priorities of Medicinal Plants near a Protected Area in Brazil

open access: yesEvidence-Based Complementary and Alternative Medicine, 2019
We investigated the influence of socioeconomic factors (age, gender, and occupation) on the local knowledge of medicinal plants in the Araripe National Forest, Brazil, and the priority of conservation of the species as perceived by people.
N. F. da Silva   +5 more
semanticscholar   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Understanding the conservation-genetics gap in Latin America: challenges and opportunities to integrate genetics into conservation practices

open access: yesFrontiers in Genetics
Introduction: Integrating genetic data into conservation management decisions is a challenging task that requires strong partnerships between researchers and managers.
Constanza Napolitano   +35 more
doaj   +1 more source

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