Results 111 to 120 of about 4,158,166 (297)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Locally Differentially Private Minimum Finding

open access: yesIEICE Transactions on Information and Systems, 2022
Kazuto FUKUCHI, Chia-Mu YU, Jun SAKUMA
openaire   +1 more source

Genetic Algorithms with Local Minimum Escaping Technique

open access: yesIEEJ Transactions on Electronics, Information and Systems, 2004
In this paper, we propose a genetic algorithm(GA) with local minimum escaping technique. This proposed method uses the local minimum escaping techique. It can escape from the local minimum by correcting parameters when genetic algorithm falls into a local minimum.
Hiroki Tamura   +3 more
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Linear statistical inference for global and local minimum variance portfolios [PDF]

open access: yes
Traditional portfolio optimization has been often criticized since it does not account for estimation risk. Theoretical considerations indicate that estimation risk is mainly driven by the parameter uncertainty regarding the expected asset returns rather
Frahm, Gabriel
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

On minimum distance of locally repairable codes

open access: yes2017 15th Canadian Workshop on Information Theory (CWIT), 2017
This paper has been withdrawn by the author due to some ...
Mehrabi, Mehrtash, Ardakani, Massoud
openaire   +2 more sources

Minimum wage and youth unemployment in local labor markets in Poland [PDF]

open access: yes, 2015
A revised and updated version of this working paper is published in the journal: ROCZNIKI KOLEGIUM ANALIZ EKONOMICZNYCH, KOLEGIUM ANALIZ EKONOMICZNYCHThe aim of the paper is to analyze the impact of minimum wage on youth unemployment (less than 25 years
Broniatowska, Paulina   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The Aronsson Equation, Lyapunov Functions, and Local Lipschitz Regularity of the Minimum Time Function

open access: yesAbstract and Applied Analysis, 2019
We define and study C1-solutions of the Aronsson equation (AE), a second order quasi linear equation. We show that such super/subsolutions make the Hamiltonian monotone on the trajectories of the closed loop Hamiltonian dynamics. We give a short, general
Pierpaolo Soravia
doaj   +1 more source

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