Results 81 to 90 of about 4,158,166 (297)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Sedimentary pyrite sulfur isotopes track the local dynamics of the Peruvian oxygen minimum zone

open access: yesNature Communications, 2021
To explore the importance of local vs. global sulfur-cycle controls on variations in pyrite sulfur isotopes, the authors couple carbon-nitrogen-sulfur concentrations and stable isotopes of sediments from the Peruvian oxygen minimum zone, identifying a ...
Virgil Pasquier   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Illegal migration, enforcement and minimum wage [PDF]

open access: yes, 2007
This paper examines the connection between illegal migration, minimum wages and enforcement policy. We first explore the employers’ decision regarding the employment of illegal migrants in the presence of an effective minimum wage.
Epstein, G.S., Heizler, O.
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Option pricing and hedging with minimum local expected shortfall

open access: yes, 2003
We propose a versatile Monte-Carlo method for pricing and hedging options when the market is incomplete, for an arbitrary risk criterion (chosen here to be the expected shortfall), for a large class of stochastic processes, and in the presence of ...
Bouchaud, Jean-Philippe   +1 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Optimal Linear Codes with a Local-Error-Correction Property

open access: yes, 2012
Motivated by applications to distributed storage, Gopalan \textit{et al} recently introduced the interesting notion of information-symbol locality in a linear code.
Kamath, Govinda M.   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An investigation of winter minimum temperatures in the mountains of Montenegro: A case study from the karst depression of Valoviti Do and selected mountain stations of northern Montenegro [PDF]

open access: yesGeographica Pannonica, 2018
This article presents the findings from measurements of winter minimum temperatures taken over a period of several years in the high mountain karst depression of Valoviti Do on the Durmitor massif (Montenegro), and compares them with temperatures ...
Ogrin Matej   +3 more
doaj  

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