Results 51 to 60 of about 11,803,797 (308)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

O governo da e pela kultura. Complexos locais de governança na formação do Estado em Timor‑Leste

Revista Crítica de Ciências Sociais, 2014
This paper discusses the ways in which the Timorese state has dealt with elements of local governance complexes called kultura. Based on the analysis of recent uses of tara bandu and the organizational dynamics of local power, the text argues that the ...
Kelly Silva
doaj   +1 more source

The Power of Local Action: Learning and Exploring Possibilities for Local Humanitarian Leadership

, 2020
The Power of Local Action is an Oxfam learning compendium on local humanitarian leadership (LHL) that arose out of learning events and global meetings held in 2019 in Nairobi, Mexico City, Jakarta and Istanbul, and draws from the ...
van den Berg, Michelle, Gray, Amy, Kergoat, Alain, Benavides de la Vega, Lourdes, Jayasinghe, Namalie, Kumar, Raman, Merelo Lobo, Mariana   +6 more
core  

What is BPA?

, 1996
This PR pamphlet explains what BPA (Bonneville Power Administration) is (a Federal agency with a Northwest focus). It plays a role in balancing river uses; power revenues pay BPA costs; renewable resource aspects are discussed; fish and wildlife ...
United States. Bonneville Power Administration.
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

L’écrit et la justice au Mont Saint-Michel : les notices narratives (vers 1060-1150)

Tabularia, 2007
The practices in the Mont as regards judiciary writings are comparable to the ones of the ligerian monasteries. The series of narrative notices kept in the cartulary begins under the rule of abbot Renouf (1055-1084/1085), thrives with abbot Bernard (1131-
Éric Van Torhoudt
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Local power flow control

Power engineering: research, equipment, technology
Show  the  prospects  for  the  development  of  local  electric  networks  with distributed generation. Recent changes in the electric power industry are forcing the revision of the  requirements  for  both  infrastructure  and  power  facilities.  Show  that  the  connection  of distributed generators and consumers of electrical energy to the network
L. M. Chetochnikova, N. I. Smolentsev, N. V. Tomskich, D. A. Gimgina, D. A. Lavrentieva   +4 more
openaire   +2 more sources

Familias, influencias y clientelismos. Una microhistoria del poder franquista en Lleida, 1938-1951

Historia Actual On-Line, 2015
A partir del estudio del caso leridano, el artículo profundiza en el conocimiento de las bases sociales sobre las que se construyó y consolidó el régimen político franquista.
Josep Gelonch Solé
doaj