Results 61 to 70 of about 11,803,797 (308)
História, 2005 Este texto apresenta algumas hipóteses e idéias sobre o comércio de abastecimento da cidade de São Paulo, entre os anos 1765-1822, através de dados quantitativos e qualitativos levantados em dois conjuntos documentais produzidos pelo Senado da Câmara ...
Denise A Soares de Moura
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The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
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Chej Maelainin, un notable sahariano
Revista de Estudios Internacionales Mediterráneos, 2011 Chorfa, Haj, Alem y santo. Chej Maelainin, último de los grandes personajes del Sáhara nació en el seno de una familia de linaje chorfa, dedicada al estudio.
Ángela Hernández Moreno
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MathematicsThis paper addresses the problem of making inferences about a common mean vector from several independent multivariate normal populations with unknown and unequal dispersion matrices. We propose an unbiased estimator of the common mean vector, along with
Yehenew G. Kifle +2 more
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BPA Prepares for the 21st Century.
, 1998 This is a brief review of the state of the Bonneville Power Administration. It reviews BPA`s competitive status, fish and wildlife funding, cost structure of the federal system, subscription sales of electricity, emergency cost recovery, cost reduction ...
United States. Bonneville Power Administration.
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Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
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FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
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Local Prediction-Powered Inference
CoRRTo infer a function value on a specific point $x$, it is essential to assign higher weights to the points closer to $x$, which is called local polynomial / multivariable regression. In many practical cases, a limited sample size may ruin this method, but such conditions can be improved by the Prediction-Powered Inference (PPI) technique.
Yanwu Gu, Dong Xia
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Cogent Social SciencesIndonesia’s village-owned enterprises (BUMDes), backed by substantial fiscal decentralization, are envisioned as catalysts for rural economic autonomy. However, many remain stagnant despite receiving significant state capital injections.
Jamal Bake +4 more
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