Results 71 to 80 of about 11,351,964 (305)

Local Prediction-Powered Inference

open access: yesCoRR
To infer a function value on a specific point $x$, it is essential to assign higher weights to the points closer to $x$, which is called local polynomial / multivariable regression. In many practical cases, a limited sample size may ruin this method, but such conditions can be improved by the Prediction-Powered Inference (PPI) technique.
Yanwu Gu, Dong Xia
openaire   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Other title: Alabama Power Company electric transmission and distribution system

open access: yes, 1954
Identifies generating plants, substations, types of transmission lines, areas served, and areas served by other ...
Alabama Power Company.
core   +1 more source

Institutional failure and the shadow of local elites: a multi-case study of problematic village enterprises in Indonesia

open access: yesCogent Social Sciences
Indonesia’s village-owned enterprises (BUMDes), backed by substantial fiscal decentralization, are envisioned as catalysts for rural economic autonomy. However, many remain stagnant despite receiving significant state capital injections.
Jamal Bake   +4 more
doaj   +1 more source

Presupuestos municipales, participación y reordenamiento de los espacios políticos [PDF]

open access: yesÍconos, 2009
Este artículo aborda los procesos de elaboración de presupuestos municipales en diez provincias del Cusco y Puno, inscribiéndose en el marco del análisis de la tensión burocrática y política entre espacios centrales (Estado) y periferias (ámbitos locales)
Alejandro Diez Hurtado
doaj  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Alabama Power Company electric transmission and distribution system

open access: yes, 1942
Identifies generating plants, substations, types of transmission lines, areas served, and areas served by other ...
Alabama Power Company.
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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