Results 61 to 70 of about 5,469,672 (300)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
1923-1938 YILLARI ARASINDA YEREL BASINDA KONYA EKONOMİSİ
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2015 Cumhuriyetin kuruluş yıllarından itibaren izlenen ekonomi politikalarına bakıldığında 1923-1929 yılları arasında nispeten liberal politikalar izlendiği, 1930-1938 yılları arasında ise devletçi politikaların ekonomide etkinlik kazandığı görülmektedir ...
Rahime Hülya Öztürk
doaj
Time-Dependent Superfluid Local Density Approximation
, 2013 The time-dependent superfluid local density approximation (TDSLDA) is an extension of the Hohenberg-Kohn density functional theory (DFT) to time-dependent phenomena in superfluid fermionic systems.
Bulgac, Aurel, Forbes, Michael McNeil
core +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
UNDERSTANDING SHIFTING LANGUAGES ON INDONESIAN TELEVISION: UNDERSTANDING SOCIAL VALUE IN LATE CAPITALISM [PDF]
, 2014 The work of Bourdieu (1991), Hobsbawm (1990), Wallerstein (2004), and Bahktin (1981), among others, have become a cornerstone for understanding valuation processes attached to language as well as their relationships with political economy and ...
Goebel, Zane
core
Stripe formation in bacterial systems with density-suppressed motility [PDF]
, 2012 Engineered bacteria in which motility is reduced by local cell density generate periodic stripes of high and low density when spotted on agar plates. We study theoretically the origin and mechanism of this process in a kinetic model that includes growth ...
Chenli Liu +7 more
core +2 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
GOGMA: Globally-Optimal Gaussian Mixture Alignment
, 2016 Gaussian mixture alignment is a family of approaches that are frequently used for robustly solving the point-set registration problem. However, since they use local optimisation, they are susceptible to local minima and can only guarantee local ...
Campbell, Dylan, Petersson, Lars
core +1 more source
XAS study of the local environment of impurities in doped TiO2 thin films [PDF]
, 2007 In this work we present an X-ray Absorption Spectroscopy characterization of the local environment of the impurity in room temperature ferromagnetic anatase TiO2 thin films doped with Co, Ni, Cu, or Zn, deposited on LaAlO3 substrate by Pulsed Laser ...
A.F. Cabrera +13 more
core +2 more sources