Results 121 to 130 of about 16,395,828 (347)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Opportunities for Local for Local Food Production: A Case in the Dutch Fruit and Vegetables

International Journal on Food System Dynamics, 2013
This paper investigates the opportunities for farmers to produce for local consumers, based on a case study in the Dutch horticulture sector. Main requirements for the set-up of a local chain of supply chain actors are investigated. Producer requirements
Jurriaan Visser, Jacques Trienekens, Paul van Beek   +2 more
doaj  

The competitiveness of cluster “Srednogorie med”: preconditions and limitations [PDF]

, 2015
Rozdział z: Functioning of the Local Production Systems in Central and Eastern European Countries and Siberia. Case Studies and Comparative Studies, ed. Mariusz E.
Slavova-Georgieva, Irena
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Experimental and numerical study on the axial compression behavior of circular concrete columns confined by BFRP spirals and ties

Reviews on Advanced Materials Science
This study investigates the compression behavior of circular concrete columns confined with basalt fiber-reinforced polymer (BFRP) stirrups, comparing their performance with traditional steel-reinforced columns.
Sufian Muhammad, Rahman Muhammad, Wang Xin, Fahmy Mohamed F.M., Wu Zhishen, Moussa Amr M.A.   +5 more
doaj   +1 more source

Local production of medical technologies and its effect on access in low and middle income countries: a systematic review of the literature

Southern Med Review, 2011
Objectives: The objective of this study was to assess the existing theoretical and empirical literature examining the link between "local production" of pharmaceuticals and medical devices and increased local access to these products.
W. Kaplan, Lindsay Sarah Ritz, M. Vitello   +2 more
semanticscholar   +1 more source

Organic agriculture development in Martinique: where does agroecological research fit in? [PDF]

, 2011
Organic agriculture is developing slowly in Martinique, a French Department in Caribbean area. In 2010, the total certified acreage reached about 100 ha, with a further 6 ha in conversion, cultivated by a total of 24 certified organic (Agriculture ...
Achard, Raphaël, Cupit, G., De Bon, Hubert, Fernandes, F., Langlais, Christian, Lavigne, Christian   +5 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Promoting sustainable agriculture in Devdaha Municipality, Nepal: leveraging agroforestry to address challenges and enhance food security

Circular Agricultural Systems
Ensuring food security through sustainable agriculture is critical for achieving the Sustainable Development Goals (SDGs). This study aimed to examine farming practices, assess the marketability of agricultural products, and propose interventions to ...
Sailesh Ranjitkar, Mohammad Ayub, Ukesh Raj Bhuju, Nani Maiya Sujakhu   +3 more
doaj   +1 more source

$e^+$ and $\bar{p}$ production in $pp$ collisions and the cosmic-ray $e^+/\bar{p}$ flux ratio

, 2017
Secondary astrophysical production of $e^+$ and $\bar{p}$ cosmic rays is considered. Inclusive $\pi$, $K$, and $\bar{p}$ production cross sections in $pp$ collisions at large $\sqrt{s}$ are parametrised using recent experimental data at LHC energies. The
Blum, Kfir, Sato, Ryosuke, Takimoto, Masahiro   +2 more
core   +1 more source