Results 101 to 110 of about 1,214,822 (266)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Influenza Vaccine Technology Transfer: A Mixed-Methods Study with Vaccine Manufacturers and Global Experts to Assess Successes, Challenges, and Opportunities

open access: yesVaccines
Background/Objectives: Technology transfer (TT) has been identified as a global health priority due to its impact on improving access to vaccines, including for pandemic influenza preparedness and response through bilateral and multilateral mechanisms ...
Christopher Chadwick   +6 more
doaj   +1 more source

Food consumption in the Canary Islands: nutritional implications of food imports and local production. [PDF]

open access: yesBMC Public Health, 2022
Godenau D   +3 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

PLAIN AND GLAZED WARE FROM THE 6TH – EARLY 7TH C. POTTERY WORKSHOP AT LOZENETS RESIDENTIAL DISTRICT, SOFIA (PRELIMINARY REPORT)

open access: yesПриноси към българската археология
The current paper aims at presenting the main pottery groups produced in the Early Byzantine pottery workshop found during rescue excavations at Lozenets residential district, Sofia, Bulgaria in 2000 – 2001. Three kilns, several pits related to them and
Evelina Todorova
doaj   +1 more source

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