Results 81 to 90 of about 2,380,854 (358)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

A Study of Physical and Mechanical Properties of the Indian Coconut for Efficient Dehusking

Journal of Natural Fibers, 2017
Coconut is a widely used fruit with soft flesh used for eating and its husk used as natural fiber. Husking is an important process in coconut processing and coir manufacturing which should be done with minimum effort. In an attempt to optimize the effort
Abi Varghese, Francis K, Jippu Jacob
doaj   +1 more source

Gaia early DR3 systemic motions of Local Group dwarf galaxies and orbital properties with a massive Large Magellanic Cloud [PDF]

, 2021
G. Battaglia, Salvatore Taibi, Guillaume F. Thomas, T. K. Fritz   +3 more
openalex   +1 more source

Regularity and nearness theorems for families of local Lie groups [PDF]

, 2011
In this work, we prove three types of results with the strategy that, together, the author believes these should imply the local version of Hilbert's Fifth problem.
McGaffey, Tom
core   +2 more sources

Non-Abelian Chern-Simons models with discrete gauge groups on a lattice

, 2005
We construct the local Hamiltonian description of the Chern-Simons theory with discrete non-Abelian gauge group on a lattice. We show that the theory is fully determined by the phase factors associated with gauge transformations and classify all possible
B Douçot, de Wild Propitius M, Dijkgraaf R, Dijkgraaf R, Doucot B, Doucot B, Feynman R P, Freed D S, Freed D S, Ioffe L B, L B Ioffe, Shor P W, Steane A, Steenrod N   +13 more
core   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Observability on the classes of non-nilpotent solvable three-dimensional Lie groups

Open Mathematics
In control theory, researchers need to understand a system’s local and global behaviors in relation to its initial conditions. When discussing observability, the main focus is on the ability to analyze the system using an output space defined by an ...
Ayala Victor, Cavalheiro Thiago Matheus, Santana Alexandre J.   +2 more
doaj   +1 more source

Abnormal Topological Organization of White Matter Structural Networks in Normal Tension Glaucoma Revealed via Diffusion Tensor Tractography

Brain Sciences, 2023
Background: Normal tension glaucoma (NTG) is considered a neurodegenerative disease with glaucomatous damage extending to diffuse brain areas. Therefore, this study aims to explore the abnormalities in the NTG structural network to help in the early ...
Yin Wang, Linying Guo, Rong Wang, Yuzhe Wang, Fei Duan, Yang Zhan, Jingfeng Cheng, Xinghuai Sun, Zuohua Tang   +8 more
doaj   +1 more source

Galaxy groups and clouds in the Local (z~0.01) universe

, 2010
We present an all-sky catalogue of 395 nearby galaxy groups revealed in the Local Supercluster and its surroundings. The groups and their associations are identified among 10914 galaxies at |b|>15deg with radial velocities VLG=4 members, is ...
Karachentsev, Igor, Makarov, Dmitry
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source