Results 91 to 100 of about 6,553,326 (307)

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Effect of bisphosphonates on local recurrence of giant cell tumor of bone: a meta-analysis

open access: yes, 2019
Mingmin Shi,1 Lei Chen,2 Yangxin Wang,1 Wei Wang,1 Yujie Zhang,1 Shigui Yan1 1Department of Orthopaedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China; 2Department of ...
Shi M   +5 more
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Adenomyoepithelioma of the breast misdiagnosed as metaplastic carcinoma in a 64-year-old female: A case report and review of literature

open access: yesJournal of Dr. NTR University of Health Sciences, 2019
Adenomyoepithelioma (AME) of the breast is a benign and indolent biphasic rare neoplasm characterized by dual proliferation of glandular and myoepithelial elements, which have propensity for local recurrences and malignant transformations. AME tumors are
I F Ezejiofor   +6 more
doaj   +1 more source

Recurrence Plots in Nonlinear Time Series Analysis: Free Software [PDF]

open access: yes
Recurrence plots are graphical devices specially suited to detect hidden dynamical patterns and nonlinearities in data. However, there are few programs available to apply such a mehodology.
Dulce Contreras, Jorge Belaire-Franch
core  

Local recurrence after retropubic radical prostatectomy for prostate cancer does not exclusively occur at the anastomotic site [PDF]

open access: yes, 2013
What's known on the subject? and What does the study add? Local recurrence after radical prostatectomy (RP) for clinically organ-confined prostate cancer is largely assumed to occur at the anastomotic site, as reflected in European and North ...
Schiller, Rike   +13 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Local Recurrence of Rectal Cancer: Risk factors, diagnosis and Quality of Life [PDF]

open access: yes
Aim To explore different aspects of local recurrence of rectal cancer, including intraoperative adverse events as a risk factor, symptoms and diagnosis, survivorship issues and Quality of Life, and to validate data on local recurrence in the Swedish ...
Waldenstedt, Sophia
core   +1 more source

Analysis of Recurrence after Frontolateral Laryngectomy [PDF]

open access: yes, 2017
Objective: This study aimed to evaluate the recurrence and survival of patients treated with frontolateral laryngectomy for T1 and T2 glottic laryngeal carcinoma.Methods: Patients who underwent frontolateral laryngectomy for glottic laryngeal carcinoma ...
Feda Bayrak   +16 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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