Results 101 to 110 of about 9,166,026 (293)

Improved Differential Evolution Algorithm to Solve the Advertising Method Selection Problem

Journal of Open Innovation: Technology, Market and Complexity, 2019
This article proposes a methodology to resolve the advertising method selection problem (AdSP). The use of different advertising methods for the same product can generate different responses in terms of the product’s sales volume. Companies selling
Malichan Thongkham, Tassin Srivarapongse
doaj   +1 more source

AVL-trees for localized search

Information and Control, 1984
We present a data structure based on AVL-trees which allows an insertion or a deletion to be performed in time O(log d), where d is the distance of the position searched for from a finger which points to the end of the file. Moving a finger to a distance d costs O(log d).
openaire   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

An Algorithm for the Euclidean Bounded Multiple Traveling Salesman Problem

Mathematics
In the Bounded Multiple Traveling Salesman Problem (BMTSP), a tour for each salesman that starts and ends at the depot and respects the bounds on the number of cities that a feasible salesman tour should satisfy is constructed.
Víctor Pacheco-Valencia, Nodari Vakhania, Federico Alonso-Pecina, José Alberto Hernández-Aguilar   +3 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A hybrid genetic algorithm and tabu search approach for post enrolment course timetabling [PDF]

, 2010
Copyright @ Springer Science + Business Media. All rights reserved.The post enrolment course timetabling problem (PECTP) is one type of university course timetabling problems, in which a set of events has to be scheduled in time slots and located in ...
Yang, S, Jat, SN, Yang, Shengxiang, Shengxiang Yang, Sadaf Naseem Jat   +4 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Use of memetic algorithms to solve a stochastic location model: health resources for diabetics in some provinces of castilla-león

Rect@, 2005
This paper applies a memetic algorithm, MA, to solve a stochastic facility location problem. This MA is constructed by combining a genetic algorithm with a local search operator. The problem consists on determining the best locations in which to place
Silvia Casado, Ada Álvarez, Jesús F. Alegre, Joaquín A. Pacheco   +3 more
doaj  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source