Results 101 to 110 of about 3,752,335 (283)
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source
TIVC: An Efficient Local Search Algorithm for Minimum Vertex Cover in Large Graphs. [PDF]
Sensors (Basel), 2023 Zhang Y, Wang S, Liu C, Zhu E.
europepmc +1 more source
Local Search Techniques for Constrained Portfolio Selection Problems
, 2001 We consider the problem of selecting a portfolio of assets that provides the investor a suitable balance of expected return and risk. With respect to the seminal mean-variance model of Markowitz, we consider additional constraints on the cardinality of ...
Schaerf, Andrea
core +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Rect@, 2005 This paper applies a memetic algorithm, MA, to solve a stochastic facility location problem. This MA is constructed by combining a genetic algorithm with a local search operator. The problem consists on determining the best locations in which to place
Silvia Casado +3 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
, 2022 AbstractIf local research constitutes the backbone of metaheuristics, tabu search, looking to learn how to iteratively modify a solution can be considered the master of metaheuristics. Moreover, this term was proposed by his inventor. This chapter focuses on the ingredients at the basis of taboo search, namely, the use of memories and tactics for ...
openaire +1 more source
Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
Modified shuffled frog-leaping algorithm to solve traveling salesman problem
Tongxin xuebao, 2009 Modified shuffled frog-leaping algorithm to solve TSP was proposed,which presented the concept of adjustment sequence to design the strategy of local searching,and added the mutation operation in the global exchange of information.Experimental results ...
LUO Xue-hui, YANG Ye, LI Xia
doaj