Results 81 to 90 of about 9,166,026 (293)
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Search Activities, Cost of Living and Local Labor Markets [PDF]
A model is considered in which optimal search intensity is a result of a trade off between short run losses due to higher search costs (more interviews, commuting...) and long-run gains due to a higher chance of finding a job.
Patacchini, Eleonora, Zenou, Yves
core
Finding the Best 3-OPT Move in Subcubic Time
Algorithms, 2020 Given a Traveling Salesman Problem solution, the best 3-OPT move requires us to remove three edges and replace them with three new ones so as to shorten the tour as much as possible.
Giuseppe Lancia, Marcello Dalpasso
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
GraphRAG on Technical Documents - Impact of Knowledge Graph Schema [PDF]
Transactions on Graph Data and KnowledgeRetrieval Augmented Generation (RAG) is seeing rapid adoption in industry to enable employees to query information captured in proprietary data for their organisation.
Scaffidi, Henri +3 more
doaj +1 more source
, 2022 AbstractImprovement methods constitute the backbone of most metaheuristics. These methods repeatedly perform slight, local modifications on a current solution to the problem. Hence, for any solution, a set of neighbor solutions must be defined. Clearly, the definition of this set depends on the problem modeling. However, a natural neighborhood may turn
openaire +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
A New Local Search for Continuous Location Problems [PDF]
, 2013 This paper presents a new local search approach for solving continuous location problems. The main idea is to exploit the relation between the continuous model and its discrete counterpart.
Mladenovic, Nenad +3 more
core +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Toward an automaton Constraint for Local Search [PDF]
, 2009 We explore the idea of using finite automata to implement new constraints for local search (this is already a successful technique in constraint-based global search). We show how it is possible to maintain incrementally the violations of a constraint and
Flener, Pierre, +5 more
core +1 more source