Results 41 to 50 of about 657,946 (259)
Applied Sciences, 2021 Several interesting libraries for optimization have been proposed. Some focus on individual optimization algorithms, or limited sets of them, and others focus on limited sets of problems.
Illya Bakurov +4 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Logistic optimization of the blood delivery routing problem in the Lower Southern region of Thailand
Engineering and Applied Science Research, 2023 This study discusses a blood delivery routing problem faced by a regional blood centre (RBC). The RBC meets the requests of 21 hospitals for blood and blood products.
Kunanon Intapan +4 more
doaj
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Discrete Optimization, 2015 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
LANCIA, Giuseppe +2 more
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
No-Wait Job Shop Scheduling Using a Population-Based Iterated Greedy Algorithm
Algorithms, 2021 When no-wait constraint holds in job shops, a job has to be processed with no waiting time from the first to the last operation, and the start time of a job is greatly restricted. Using key elements of the iterated greedy algorithm, this paper proposes a
Mingming Xu +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Evolutionary Multi-objective Optimization for Multi-depot Vehicle Routing in Logistics
International Journal of Computational Intelligence Systems, 2017 Delivering goods in an efficient and cost-effective way is always a challenging problem in logistics. In this paper, the multi-depot vehicle routing is focused. To cope with the conflicting requirements, an advanced multi-objective evolutionary algorithm
Xiaowen Bi, Zeyu Han, Wallace K. S. Tang
doaj +1 more source
Scheduling Algorithms for a Hybrid Flow Shop under Uncertainty
Algorithms, 2020 In modern production systems, scheduling problems have to be solved in consideration of frequently changing demands and varying production parameters.
Christin Schumacher, Peter Buchholz
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