ON THE VARIANCE OF LOCAL STEREOLOGICAL VOLUME ESTIMATORS
Image Analysis and Stereology, 2011 In the present paper, the variance of local stereological volume estimators is studied. For isotropic designs, the variance depends on the shape of the body under study and the choice of reference point. It can be expressed in terms of an equivalent star
Eva B Vedel Jensen
doaj +4 more sources
FURTHER RESULTS ON VARIANCES OF LOCAL STEREOLOGICAL ESTIMATORS
Image Analysis and Stereology, 2011 In the present paper the statistical properties of local stereological estimators of particle volume are studied. It is shown that the variance of the estimators can be decomposed into the variance due to the local stereological estimation procedure and ...
Zbyněk Pawlas, Eva B Vedel Jensen
doaj +5 more sources
Wicksell's Problem in Local Stereology [PDF]
Advances in Applied Probability, 2013 Wicksell's classical corpuscle problem deals with the retrieval of the size distribution of spherical particles from planar sections. We discuss the problem in a local stereology framework. Each particle is assumed to contain a reference point and the individual particle is sampled with an isotropic random plane through this reference point.
Ó. Thórisdóttir, Markus Kiderlen
+7 more sources
Counting glomeruli in human kidney specimens using ex vivo MRI without contrast agents. [PDF]
Magn Reson MedAbstract Purpose The total number of glomeruli is an important indicator of kidney function and susceptibility to disease. Glomeruli, however, are difficult to image using MRI without contrast enhancement. For this reason, previous studies have used cationic ferritin as a contrast agent to detect glomeruli in ex vivo and in vivo perfused kidneys.
Kurniawan ND +11 more
europepmc +2 more sources
Prenatal fructose exposure independently impacts placental phenotype and female offspring kidney function and liver composition in rats. [PDF]
Physiol RepAbstract Archaeological and anthropological evidence suggests that human ancestors' diets were rich in fiber, potassium, and complex carbohydrates, while low in sodium, refined sugars, and energy density. Over time, agroindustrialization led to diets poorer in fiber and micronutrients but higher in sodium, simple sugars, and calorie‐dense foods.
Coppi AA +5 more
europepmc +2 more sources
Morphophysiology and Hormonal Control of the Mammary Gland of the Bat Artibeus lituratus During Gestation and Lactation: Emphasis on Estradiol and Progesterone. [PDF]
J MorpholThe mammary gland of NON females of Artibeus lituratus was composed of few ducts interspersed within a rich stroma, and covered by adipose tissue. The branching of the mammary gland in AP females are triggered by stimuli from an increase in serum estradiol that, through ERα activation, stimulates the proliferation of the ducts, and an increase in serum
Santiago CS +9 more
europepmc +2 more sources
Localization of Macrophages in the Human Lung Via Design-Based Stereology [PDF]
A67. STRUCTURE-FUNCTION RELATIONSHIPS, 2020 Rationale: Interstitial macrophages (IMs) and airspace macrophages (AMs) play critical roles in lung homeostasis and host defense, and are central to the pathogenesis of a number of lung diseases. However, the absolute numbers of macrophages and the precise anatomic locations they occupy in the healthy human lung have not been quantified.Objectives: To
Patrick S. Hume +7 more
openaire +3 more sources
Phthalate Exposure During Pregnancy and Lactation Transgenerationally Impairs the Epididymis in the Offspring of Rats. [PDF]
J Biochem Mol ToxicolThis study reveals that phthalate exposure induces tissue remodeling and alters gene expression in the epididymis of Sprague‐Dawley rats across two generations. The findings underscore the transgenerational impact of phthalates, highlighting their influence on oxidative stress and inflammatory pathways during critical developmental windows.
Punhagui-Umbelino APF +8 more
europepmc +2 more sources
On the Applicability of Stereological Methods for the Modelling of a Local Plastic Deformation in Grained Structure: Mathematical Principles [PDF]
Crystals, 2020 Analysis of systems and structures from their cross-sectional images finds applications in many branches. Therefore, the question of content, quantity, and accuracy of information obtained from various techniques based on cross-sectional views of structures is particularly important. Application of conventional techniques for two-dimensional imaging on
Minárik, Martinkovič
openaire +1 more source
Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons. [PDF]
, 2017 Increased α-synuclein (αsyn) and mitochondrial dysfunction play central roles in the pathogenesis of Parkinson's disease (PD), and lowering αsyn is under intensive investigation as a therapeutic strategy for PD. Increased αsyn levels disrupt mitochondria
Bendor, Jacob T +9 more
core +1 more source