Results 221 to 230 of about 1,706,702 (287)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Foreign body-associated maxillary sinus aspergillosis caused by Endomethasone extrusion: diagnostic challenges, biological mechanisms, and surgical management. [PDF]

J Oral Biol Craniofac Res
Zubair Ahemad A, Singh TK, Gupta A, Choudhary E.   +3 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

RFID Technology for Intraoperative Localisation of Small Colorectal Tumours: Electromagnetic Analysis and Experimental Validation. [PDF]

Diagnostics (Basel)
Mocan B, Mocan M, Fulea M, Murar M, Mate Z, Calborean A, Bintintan VV.   +6 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Navigating regulatory fragmentation in the convergence of synthetic biology, artificial intelligence, and automation. [PDF]

Nat Commun
McLennan RKJ, Freemont PS, Pretorius IS.
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Diagnostic accuracy of ChatGPT for 12-lead ECG-based localisation of ventricular ectopic foci prior to catheter ablation. [PDF]

Front Med (Lausanne)
Gürses KM, Tezcan H, Yalçın MU, Özalp H, Tunçez A, Özen Y.   +5 more
europepmc   +1 more source

Observer-conditioned complexity minimisation selects the Standard Model with right-handed neutrinos: and localises the boundary between law and address

We perform an exhaustive, pre-registered search over the Wedderburn-classified finite real spectral triples of noncommutative geometry, ranking candidates by frozen prefix-free description-length measures. Bare complexity minimisation fails to select the Standard Model.
openaire   +1 more source