Results 51 to 60 of about 274,387 (252)

Multi-site breathers in Klein-Gordon lattices: stability, resonances, and bifurcations

, 2013
We prove the most general theorem about spectral stability of multi-site breathers in the discrete Klein-Gordon equation with a small coupling constant.
Anton Sakovich, Bambusi D, Broer H, Dmitry Pelinovsky, James G, Kato T, Koukouloyannis V, MacKay R S, Simo C, Yakubovich V A, Yoshimura K, Zeidler E   +11 more
core   +1 more source

Polyharmonic homogenization, rough polyharmonic splines and sparse super-localization [PDF]

, 2013
We introduce a new variational method for the numerical homogenization of divergence form elliptic, parabolic and hyperbolic equations with arbitrary rough ($L^\infty$) coefficients.
Berlyand, Leonid, Owhadi, Houman, Zhang, Lei   +2 more
core   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Tectonic transition and extension at the eastern and western ends of the Altyn Tagh fault: insights from triple junctions

Dizhi lixue xuebao
Objective  The Altyn Tagh fault (ATF) is the largest left-lateral strike-slip fault on the northern margin of the Qinghai-Tibet Plateau, extending for about 1600 km.
YI Kexin, JOLIVET Marc, GUO Zhaojie
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Heat Transfer in n‐Dimensional Parallelepipeds Under Zero Dirichlet Conditions

Engineering Reports
This article presents a comprehensive analytical study of heat propagation in an n‐dimensional bounded domain subject to zero Dirichlet boundary conditions, corresponding to a thermally insulated parallelepiped with internal heat sources. While classical
Zafar Duman Abbasov, Davron Aslonqulovich Juraev, Obidjon Khayrullaevich Abdullaev, Irfan Nurhidayat, Mohd Asif Shah   +4 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Two-dimensional ring-like vortex and multisoliton nonlinear structures at the upper-hybrid resonance

, 2007
Two-dimensional (2D) equations describing the nonlinear interaction between upper-hybrid and dispersive magnetosonic waves are presented. Nonlocal nonlinearity in the equations results in the possibility of existence of stable 2D nonlinear structures.
Kolchugina I. A., Petviashvili V. I., V. M. Lashkin, Zakharov V. E., Zakharov V. E.   +4 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source