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Localized Scleroderma

Current Opinion in Rheumatology, 1989
Localized scleroderma has no recognized internal organ involvement. It may rarely coexist with a systemic connective tissue disease, but is not thought to progress to systemic sclerosis. Although never fatal, localized scleroderma may cause considerable disability from joint contractures and subcutaneous atrophy.
Vincent Falanga
  +7 more sources

Immunopathogenesis of Pediatric Localized Scleroderma. [PDF]

Front Immunol, 2019
Localized scleroderma (LS) is a complex disease characterized by a mixture of inflammation and fibrosis of the skin that, especially in the pediatric population, also affects extracutaneous tissues ranging from muscle to the central nervous system. Although developmental origins have been hypothesized, evidence points to LS as a systemic autoimmune ...
Torok KS, Li SC, Jacobe HM, Taber SF, Stevens AM, Zulian F, Lu TT.   +6 more
europepmc   +6 more sources

Connective tissue nevus misdiagnosed as juvenile localized scleroderma. [PDF]

Pediatr Rheumatol Online J, 2023
Tirelli F, Giraudo C, Soliani M, Calabrese F, Martini G, Gisondi P, Meneghel A, Zulian F.   +7 more
europepmc   +3 more sources

Mycophenolate mofetil for methotrexate-resistant juvenile localized scleroderma. [PDF]

Rheumatology (Oxford), 2021
Martini G, Saggioro L, Culpo R, Vittadello F, Meneghel A, Zulian F.   +5 more
europepmc   +3 more sources

Genetic Signatures From RNA Sequencing of Pediatric Localized Scleroderma Skin. [PDF]

Front Pediatr, 2021
Mirizio E, Liu C, Yan Q, Waltermire J, Mandel R, Schollaert KL, Konnikova L, Wang X, Chen W, Torok KS.   +9 more
europepmc   +3 more sources

Localized scleroderma and scleroderma-like syndromes

, 2015
Robert W. Simms
openalex   +2 more sources

Correction to: Single-cell transcriptome conservation in a comparative analysis of fresh and cryopreserved human skin tissue: pilot in localized scleroderma. [PDF]

Arthritis Res Ther, 2021
Mirizio E, Tabib T, Wang X, Chen W, Liu C, Lafyatis R, Jacobe H, Torok KS.   +7 more
europepmc   +3 more sources

Successful treatment of localized scleroderma using brodalumab: A case report. [PDF]

SAGE Open Med Case Rep
Bobica AC, Zhu C, Silotch C, BinJadeed H, Netchiporouk E.   +4 more
europepmc   +2 more sources

Incidence, prevalence, and mortality of localized scleroderma in Quebec, Canada: a population-based study. [PDF]

Lancet Reg Health Am
Ghazal S, Muntyanu A, Aw K, Kaouache M, Khoury L, Piram M, McCuaig C, Chédeville G, Rahme E, Osman M, Schachter J, Bertrand J, Netchiporouk E.   +12 more
europepmc   +2 more sources

Case Report: Exacerbation after fat grafting in patients with active localized scleroderma. [PDF]

Front Surg
Han S, Liu J, Lu F, Cai J.
europepmc   +2 more sources