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Morphea (Localized Scleroderma)
2016Morphea, also called localized scleroderma, is a sclerosing skin disorder that resembles scleroderma (systemic sclerosis) in terms of cutaneous histopathological features, but differs demographically and clinically. Hallmark clinical and serological features of scleroderma (sclerodactyly, Raynaud’s phenomenon, internal organ involvement, and ...
Noelle M. Teske, Heidi T. Jacobe
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Borrelia burgdorferi and Localized Scleroderma
Archives of Dermatology, 1989To the Editor.— Aberer et al, 1 in Austria, have suggested that morphea might be related to Borrelia burgdorferi infection. These authors found antibodies to B burgdorferi in five of ten patients with morphea in one study and eight of 15 patients in another study, which used the enzyme-linked immunosorbent assay.
Martine Bagot +4 more
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Localized scleroderma: Imaging features
Pediatric Radiology, 1994Localized scleroderma is distinct from the diffuse form of scleroderma and does not show Raynaud's phenomenon and visceral involvement. The imaging features in 23 patients ranging from 2 to 17 years of age (mean 11.1 years) were reviewed. Leg length discrepancy and muscle atrophy were the most common findings (five patients), with two patients also ...
P. Liu +5 more
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Localized Scleroderma in a Child
2011Localized scleroderma (morphea) is much more common than systemic sclerosis (SSc) in childhood and is classified based on the Pediatric Rheumatology European Society Consensus meeting into circumscribed, linear (may involve extremity or head) generalized, pansclerotic, and mixed. Linear is the most common form in childhood.
Christine O’Brien +2 more
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Classification of Morphea (Localized Scleroderma)
Mayo Clinic Proceedings, 1995To classify and describe morphea (localized scleroderma).A review of morphea and its subtypes is presented.The current classification of morphea is incomplete and confusing. As knowledge of the spectrum of disease continues to evolve, the controversy and confusing nature of its multiple subtypes present a challenge for the physician who encounters a ...
Audrey M. Nelson +2 more
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Recurrent myelitis in localized scleroderma
Clinical Neurology and Neurosurgery, 2014Localized scleroderma is a rare disorder which has an annual ncidence rate of less than 3 per 100,000 population [1]. Historically, ocalized scleroderma has been divided into three types: morphea, eneralized morphea, and linear scleroderma. When a linear lesion nvolves the face or scalp, it is referred to as en coup de sabre scleoderma, and when ...
Masako Kinoshita +3 more
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LOCALIZED SCLERODERMA WITH BULLAE
Archives of Dermatology, 1941The occurrence of bullae with scleroderma is sufficiently rare to justify reporting a case of this kind. REPORT OF A CASE Mrs. F. W., an American aged 23, was referred to me during the eighth month of pregnancy by Dr. Dorothy Allen because of coin-sized lesions on her back, chest and abdomen.
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Morphea and localized scleroderma in children
Seminars in Cutaneous Medicine and Surgery, 1999Localized scleroderma refers to a diverse spectrum of disorders that involve fibrosis of the skin. Children are more likely than adults to develop localized forms of scleroderma. This condition may have devastating effects on growth and development such as limb asymmetry, flexion contractures, and psychological disability. The pathogenesis of localized
Bari B. Cunningham, Elizabeth Vierra
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New developments in localized scleroderma
Current Opinion in Rheumatology, 2008Localized scleroderma, also known as morphea, is the most frequent form of scleroderma in childhood. Early diagnosis, appropriate assessment and effective treatment may improve the long-term outcome.Recent studies, regarding the microchimerism theory or the mechanism of action of phototherapy, have yielded important information on the disease ...
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Glycosaminoglycans in Localized Scleroderma (Morphoea)
Connective Tissue Research, 1985The composition of glycosaminoglycans (GAGs) was analyzed in skin samples of eight patients suffering from localized scleroderma, i.e., three having generalized morphoea and five localized morphoea plaques. From each patients, biopsies were obtained from sclerotic and perilesional areas, and from clinically uninvolved skin of the same region.
Rigmor Møller +2 more
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