Results 21 to 30 of about 1,473,215 (222)

Application of an iPSC-Derived Organoid Model for Localized Scleroderma Therapy. [PDF]

open access: yesAdv Sci (Weinh), 2022
Localized scleroderma (LoS) is a rare chronic disease with extensive tissue fibrosis, inflammatory infiltration, microvascular alterations, and epidermal appendage lesions.
Ma J   +16 more
europepmc   +2 more sources

Clinical and laboratory characterization of patients with localized scleroderma and response to UVA-1 phototherapy: In vivo and in vitro skin models. [PDF]

open access: yesPhotodermatol Photoimmunol Photomed, 2022
Localized scleroderma (LS) is a rare disease leading to progressive hardening and induration of the skin and subcutaneous tissues. LS is responsive to UVA‐1 phototherapy, though its exact mechanism of action dermal fibrosis is yet to be fully elucidated.
Tognetti L   +6 more
europepmc   +2 more sources

Genetic Signatures From RNA Sequencing of Pediatric Localized Scleroderma Skin. [PDF]

open access: yesFront Pediatr, 2021
The purpose of this study was to explore the skin transcriptional profile in pediatric localized scleroderma (LS) to provide a better understanding of the altered immune and fibrotic pathways promoting disease. LS is a progressive disease of the skin and
Mirizio E   +9 more
europepmc   +2 more sources

The Anti-Fibrotic Effect of Cold Atmospheric Plasma on Localized Scleroderma In Vitro and In Vivo. [PDF]

open access: yesBiomedicines, 2021
Cold Atmospheric Plasma (CAP) has shown promising results in the treatment of various skin diseases. The therapeutic effect of CAP on localized scleroderma (LS), however, has not yet been evaluated.
Arndt S   +4 more
europepmc   +2 more sources

Localized scleroderma: clinical spectrum and therapeutic update [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2015
Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis ...
Mariana Figueiroa Careta, Ricardo Romiti
doaj   +2 more sources

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