Results 111 to 120 of about 4,204,651 (354)

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

Recent advances in local anaesthesia [PDF]

Canadian Anaesthetists’ Society Journal, 1986
In general, the cardiovascular system is more resistant to the toxic actions of local anaesthetics than is the central nervous system. However, if sufficient doses and blood levels of local anaesthetics are achieved, signs of profound cardiovascular depression may be observed.
openaire   +2 more sources

Novel schedule for treatment of inflammatory breast cancer [PDF]

, 2016
Inflammatory breast cancer (IBC) is the most aggressive form of this tumor, with the clinical and biological characteristics of a rapidly proliferating disease.
Cefalì, K, Corvino, R, D'Aniello, D, De Iuliis, F, Lanza, R, Scarpa, Susanna   +5 more
core  

Effect of Laparoscopic vs Open Distal Gastrectomy on 3-Year Disease-Free Survival in Patients With Locally Advanced Gastric Cancer: The CLASS-01 Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2019
Importance Laparoscopic distal gastrectomy is accepted as a more effective approach to conventional open distal gastrectomy for early-stage gastric cancer. However, efficacy for locally advanced gastric cancer remains uncertain.
Jiang Yu, Chang-ming Huang, Yihong Sun, X. Su, H. Cao, Jian-kun Hu, Kuan Wang, J. Suo, K. Tao, Xianli He, Hongbo Wei, M. Ying, Wei-guo Hu, Xiao-hui Du, Yanfeng Hu, Hao Liu, C. Zheng, Ping Li, Jian-Wei Xie, Fenglin Liu, Ziyu Li, Gang Zhao, Kun Yang, Chunxiao Liu, Haojie Li, Pingyan Chen, J. Ji, Guoxin Li   +27 more
semanticscholar   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

The role of chemoradiotherapy and immunotherapy in stage III NSCLC

Pathology and Oncology Research
Locally advanced non-small lung cancer encompasses a diverse range of tumors. In the last few years, the treatment of stage III unresectable non-small lung cancer has evolved significantly.
Zsuzsanna Orosz, Árpád Kovács
doaj   +1 more source

Locally advanced lung cancer [PDF]

CA: A Cancer Journal for Clinicians, 2021
Arafat H. Tfayli, Pierre M. Sfeir, Bassem Y. Youssef, Fadlo R. Khuri   +3 more
openaire   +2 more sources

A phase II study of capecitabine and oxalplatin combination chemotherapy in patients with inoperable adenocarcinoma of the gall bladder or biliary tract [PDF]

, 2016
Background: Advanced biliary tract carcinomas are associated with a poor prognosis, and palliative chemotherapy has only modest benefit. This multi-centre phase II study was conducted to determine the efficacy of capecitabine in combination with ...
E. Soulis, F. Y. Coxon, J. S. Graham, K. Boyd, L. R. Wall, M. Highley, M. M. Eatock, P. Bützberger-Zimmerli, S. Harden, T. R. J. Evans, T. S. Maughan   +10 more
core   +1 more source

Circulating tumor DNA dynamics predict benefit from consolidation immunotherapy in locally advanced non-small-cell lung cancer

Nature Cancer, 2020
Circulating tumor DNA (ctDNA) molecular residual disease (MRD) following curative-intent treatment strongly predicts recurrence in multiple tumor types, but whether further treatment can improve outcomes in patients with MRD is unclear. We applied cancer
E. Moding, Yufei Liu, B. Nabet, J. Chabon, A. Chaudhuri, A. Hui, Rene F Bonilla, R. Ko, C. Yoo, Linda Gojenola, Carol Jones, Jianzhong He, Y. Qiao, T. Xu, J. Heymach, A. Tsao, Z. Liao, D. Gomez, M. Das, S. Padda, K. Ramchandran, J. Neal, H. Wakelee, B. Loo, Steven H. Lin, Ash A. Alizadeh, M. Diehn   +26 more
semanticscholar   +1 more source