Local advancement flaps
Doublet chemotherapy, triplet chemotherapy, or doublet chemotherapy combined with radiotherapy as neoadjuvant treatment for locally advanced oesophageal cancer (JCOG1109 NExT): a randomised, controlled, open-label, phase 3 trial
Local and Locally Advanced Rectal Cancer
Randomised trial of surgery alone versus radiotherapy followed by surgery for potentially operable locally advanced rectal cancer