Results 221 to 230 of about 19,218 (261)

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

open access: yesAndrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis   +3 more
wiley   +1 more source

Surveillance After Pelvic Exenteration: A Systematic Review of Oncological and Functional Follow‐Up

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background Surveillance following cancer surgery with curative intent serves the purpose of permitting early detection of recurrent disease in addition to monitoring and management of post‐resection functional sequelae. Although recommendations exist for most primary cancers, in the context of radical or re‐operative surgery such as pelvic ...
Adrian Hang Yue Siu   +5 more
wiley   +1 more source

Updates in Management of Locally and Regionally Advanced Basal Cell Carcinoma

open access: yesSurgical Clinics of North America
Basal cell carcinoma (BCC) is a slow-growing skin cancer that tends to remain localized but that can occasionally grow extensively and penetrate deeper tissues (locally advanced BCC [laBCC]). The first line of treatment for laBCC is surgical excision, but when resection is not possible systemic therapies such as Hedgehog pathway inhibitors or immune ...
Kristel Lourdault, Richard Essner
exaly   +4 more sources

Cemiplimab for locally advanced and metastatic basal cell carcinoma

Expert Review of Anticancer Therapy, 2022
Locally advanced basal cell carcinoma (laBCC) represents approximatively 1% of all BCCs. Metastatic BCC (mBCC) is even more rare. Most cases are observed in immunocompromised patients, particularly solid organ transplant recipients (OTRs). When surgery and/or radiation therapy for laBCC or mBCC is not reasonable, oral hedgehog inhibitor (HHI) therapy ...
Eve Lebas, Andree Rorive
exaly   +4 more sources

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