Results 221 to 230 of about 8,380,026 (270)

Contemporary Treatment Patterns in Surgically Treated Temporal Bone Cancer

The Laryngoscope, EarlyView.
In a national cohort of 811 surgically treated temporal bone cancer patients, adjuvant radiation therapy was the most frequently utilized postoperative treatment (20.3%), while chemotherapy and immunotherapy were used far less frequently. Multimodal treatment, particularly combined parotidectomy and neck dissection, was strongly associated with higher ...
Raquel Rowell, Christopher Z. Wen, Vera Bzhilyanskaya, Jane Y. Tong, Adam C. Kaufman   +4 more
wiley   +1 more source

Visual Parathyroid Identification in Thyroidectomy: A Decision Curve Analysis of Gland Preservation

The Laryngoscope, EarlyView.
Intraoperative visual identification remains the standard approach to parathyroid preservation during thyroidectomy, yet its accuracy has rarely been quantified against an objective reference. Among 50 suspected parathyroid specimens verified by fine‐needle aspiration PTH washout, expert consensus visual identification achieved 84.0% sensitivity but ...
Paveena Pithuksurachai, Warut Pongsapich, Noppadon Triprateepsilp, Cheerasook Chongkolwatana, Narin Ratanaprasert, Sanyaluck Wattanachalermyos   +5 more
wiley   +1 more source

EHR‐Integrated Synoptic Operative Reporting for Head and Neck Oncologic Surgery

The Laryngoscope, EarlyView.
EHR‐integrated synoptic operative templates for head and neck oncologic surgery was developed and implemented at a tertiary academic cancer center. Departmental adherence rose from 49% to nearly 80% over 6 months, and 94.5% of reviewed cases met targets for complete, internally consistent documentation. The resulting structured data dictionary provides
Miriam N. Lango, Avery Sinnathamby, Marc‐Elie Nader, Paul W. Gidley, Karen Y. Choi, Mark Zafereo, Carly E. A. Barbon, Kristen B. Pytynia, Anastasios Maniakas, Amy Hessel, Ryan P. Goepfert, Faisal I. Ahmad, Jennifer L. Anderson, Sahil K. Kapur, Jolyn S. Taylor   +14 more
wiley   +1 more source

Oncologic Outcomes in p16‐Positive Oropharyngeal Squamous Cell Carcinoma With Extranodal Extension

The Laryngoscope, EarlyView.
In this retrospective cohort of 232 surgically treated patients with p16‐positive oropharyngeal squamous cell carcinoma, survival outcomes were high and recurrence rates low. Macroscopic histopathologic extranodal extension (pENE) demonstrated lower 5‐year overall survival compared to microscopic pENE (80.2% vs. 89.8%), although this difference was not
Victoria Taylor, Colin MacKay, S. Mark Taylor, Jonathan Trites, Ayham Al Afif, Adrian Mendez, Matthew H. Rigby   +6 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

NET‐Associated Inflammatory Markers in Head and Neck Squamous Cell Carcinoma: Bioinformatic Prioritization and Exploratory Serum Assessment in Patients Undergoing Radiotherapy

Molecular Carcinogenesis, EarlyView.
ABSTRACT Neutrophil extracellular traps (NETs) and inflammatory mediators have been implicated in head and neck squamous cell carcinoma, but their relationship with systemic inflammatory status during radiotherapy remains incompletely understood. This exploratory integrative study combined a literature‐guided network‐based bioinformatic prioritization ...
Eloa Mangabeira Santos, Daniela Fernanda de Freitas, David Fernando Colón, Rangel Leal Silva, Alfredo Maurício Batista de Paula, Lucyana Conceição Farias, Bruno Rodrigues Gonçalves, Andréia Luiza Oliveira Costa, Sérgio Henrique Sousa Santos, Fernando Queiroz Cunha, Donald Fernandes, André Luiz Sena Guimarães   +11 more
wiley   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source

Giant Keratinocyte Carcinomas: Clinical, Histopathological, Molecular and Health-System Factors with Therapeutic Implications-A Structured Narrative Review. [PDF]

Cancers (Basel)
Ciborek A, Krauss H, Chęcińska-Maciejewska Z, Jaworek AK.   +3 more
europepmc   +1 more source

Giant neglected cutaneous squamous cell carcinoma of the scalp with full-thickness calvarial erosion and early fatal outcome: CT findings and treatment-planning implications. [PDF]

Radiol Case Rep
El Hassani N, Amar S, Jroundi L, El Aoufir O.   +3 more
europepmc   +1 more source