Results 91 to 100 of about 35,508,392 (286)

Social delay-tolerant network routing [PDF]

open access: yes, 2011
Paper presented at the 2nd ICC Winter Workshop on Complexity in Social SystemsRouting in mobile delay-tolerant networks faces new challenges such as mobility and the dynamic nature of the network.
Bigwood, Gregory John   +2 more
core   +2 more sources

Multi-Context Integrated Deep Neural Network Model for Next Location Prediction

open access: yesIEEE Access, 2018
The prediction of next location for users in location-based social networks has become an increasing significant requirement since it can benefit both users and business.
Jianxin Liao   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

An Agent-based Model of Retail Location with Complementary Goods [PDF]

open access: yes
This paper examines the emergence of retail clusters on a supply chain network comprised of suppliers, retailers, and consumers. An agent-based model is proposed to investigate retail location distribution in a market of two complementary goods.
Arthur Huang, David Levinson
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The Distinctiveness of Social Resrouce Theory: Positional Network and Resource Hierarchy

open access: yes, 2012
[[abstract]]There are theoretical dissonances in social resource theory. I argue that social resource theory is based on a distinct conception of network utilization, which is incompatible with Granovetter's theoretical logic of the exclusive function of
Lu-lin Cheng
core  

COMPLEX METHOD OF DETERMINING THE LOCATION OF SOCIAL NETWORK AGENTS IN THE INTERESTS OF INFORMATION OPERATIONS

open access: yesСучасні інформаційні системи
The researcher developed a method for determining the location of social network agents in the interest of conducting an information operation based on a comprehensive approach to data analysis of the information system.
Serhii Herasymov   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

A Location-based Personal Task Management Application for Indoor and Outdoor Environments

open access: yes, 2012
Personal task management has been essential for modern people, in order to remind them of something at a specific condition. Reminders based on the electronic calendar in cell phones are popular, but such reminders are mostly triggered by time.
Lin, Chi-yi; Hung, Ming-tze; Huang, Wei-hsun   +1 more
core   +1 more source

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