Results 111 to 120 of about 1,094,283 (268)

Sequential Estimation of a Common Location Parameter of two Populations

open access: yesRevstat Statistical Journal, 2016
The problem of sequentially estimating a common location parameter of two independent populations from the same distribution with an unknown location parameter and known but different scale parameters is considered in the case when the observations ...
Agnieszka Stępień-Baran
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Location Independent Manufacturing – A Software Solution for Supply Chains

open access: yesProcedia Manufacturing, 2017
Abstract One possible solution to the challenges of globalization, sustainability and the upcoming megatrends is the Location Independent Manufacturing (LIM) concept. The LIM concept is a new manufacturing philosophy that has gotten the attention of Finnish SMEs.
Merja Peltokoski   +2 more
openaire   +1 more source

Remote device access in the new accelerator controls middleware [PDF]

open access: yes, 2001
This paper presents the Remote Device Access (RDA) package developed at CERN in the framework of the joint PS/SL Controls Middleware project. The package design reflects the Accelerator Device Model in which devices, named entities in the control system,
Baggiolini, V   +5 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Valve recession: From experiment to predictive model

open access: yes, 2004
Increasing demands on engine performance and cost reductions have meant that advances made in materials and production technology are often outpaced This frequently results in wear problems occurring with engine components.
Brooks, A.   +3 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The GLASS project: supporting secure shibboleth-based single sign-on to campus resources [PDF]

open access: yes, 2007
Higher and Further education institutions in the UK are in the process of migrating their IT infrastructures to exploit Shibboleth technologies for federated access management. Ease of use and secure access are paramount to the successful uptake of these
Jiang, J., Sinnott, R.O., Watt, J.
core   +2 more sources

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