Results 111 to 120 of about 1,094,283 (268)
Sequential Estimation of a Common Location Parameter of two Populations
The problem of sequentially estimating a common location parameter of two independent populations from the same distribution with an unknown location parameter and known but different scale parameters is considered in the case when the observations ...
Agnieszka Stępień-Baran
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Location Independent Manufacturing – A Software Solution for Supply Chains
Abstract One possible solution to the challenges of globalization, sustainability and the upcoming megatrends is the Location Independent Manufacturing (LIM) concept. The LIM concept is a new manufacturing philosophy that has gotten the attention of Finnish SMEs.
Merja Peltokoski +2 more
openaire +1 more source
Remote device access in the new accelerator controls middleware [PDF]
This paper presents the Remote Device Access (RDA) package developed at CERN in the framework of the joint PS/SL Controls Middleware project. The package design reflects the Accelerator Device Model in which devices, named entities in the control system,
Baggiolini, V +5 more
core
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Valve recession: From experiment to predictive model
Increasing demands on engine performance and cost reductions have meant that advances made in materials and production technology are often outpaced This frequently results in wear problems occurring with engine components.
Brooks, A. +3 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The GLASS project: supporting secure shibboleth-based single sign-on to campus resources [PDF]
Higher and Further education institutions in the UK are in the process of migrating their IT infrastructures to exploit Shibboleth technologies for federated access management. Ease of use and secure access are paramount to the successful uptake of these
Jiang, J., Sinnott, R.O., Watt, J.
core +2 more sources

