Results 101 to 110 of about 3,756,771 (293)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Micro-computed tomography to visualize preserved vascular architecture in decellularized human vaginal tissue: explorative study

Scientific Reports
When a vagina is dysfunctional or absent, a neovagina is typically created using an intestinal or dermal graft. This causes complications and complaints from different inherent tissue properties.
Jayson Sueters, Daniel Docter, Freek Groenman, Sophie C. Visser, Bernadette S. de Bakker, Theo H. Smit, Judith A. F. Huirne   +6 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Broadband Ultrasonic Location Systems for Improved Indoor Positioning [PDF]

, 2006
Ultrasonic location systems are a popular solution for the provision of fine-grained indoor positioning data. Applications include enhanced routing for wireless networks, computer-aided navigation, and location-sensitive device behavior. However, current
Mike Hazas, Hopper, Andy, Andy Hopper, Hazas, Michael   +3 more
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Privacy in Location based Systems [PDF]

, 2018
Recent advancements in technology have opened new avenues for services like the Location based services. Location based services are applications of mobile technology that utilize the information about the location of the user.
Kalesanwo Olamide
core   +1 more source

Platelets induce epithelial to mesenchymal transition in renal proximal tubular epithelial cells through TGF-β signaling pathway

Molecular Medicine
Background Management of chronic kidney disease (CKD) remains a major challenge due limited therapeutic options to reverse fibrosis, which is a critical feature in CKD. Partial epithelial-to-mesenchymal transition (EMT) of tubular epithelial cells (TECs)
Ukhti Jamil Rustiasari, Melissa Uil, Xiaomeng Zhang, Nike Claessen, Loes Butter, Sandrine Florquin, Alessandra Tammaro, Joris J.T.H. Roelofs   +7 more
doaj   +1 more source

Location, Location, Location [PDF]

ChemMedChem, 2011
Kozikowski, A., Botta, Maurizio
openaire   +4 more sources

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Family Location Service collection 1924, 1942-1964 [PDF]

This collection consists of annual reports, name change announcements, invitations, programs for miscellaneous events, and general informational pamphletsThe Family Location Service was established in 1905 under the name of the National Desertion ...
Family Location Service (formerly National Desertion Bureau)
core