Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
WSAmacd handbook 2012-13 PDF edition [PDF]
The story, syllabus and course information handbook for the MA in Communication Design at Winchester School of Art.
Caplan, Paul
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
'Scratch' locative audio drama - report to BBC executives on trial at BBC FreeThinking 2008 [PDF]
‘Scratch’ investigates the use of physical space as a representation of narrative and dramatic structure. An audio-drama, it is a world-first in being location-sensitive without being tied to any particular place (preceding attempts by others have ...
Boyd Davis, Stephen
core
Locative Histories: exploring the continued influence of early Locative Media Art
This paper, which draws on aspects of my doctoral research, traces the influence of early Locative Media Art on the current form and application of location-aware technologies. The mechanisms and impulse for this influence are introduced and analyzed and it is proposed that they point to new approaches in the consideration of the agency of Locative ...
openaire +3 more sources
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Mapping Geomedia Studies: Origins, Trajectories, and Future Directions
This article explores the formation of and future avenues for geomedia studies. Drawing on a citation network analysis, we map the development of the interdisciplinary research terrain from its origins and identify central citation clusters.
André Jansson, Christian S. Ritter
doaj +1 more source
Supporting the consumption and co-authoring of locative media experiences for a rural village community: design and field trial evaluation of the SHARC2.0 framework. [PDF]
Cheverst K, Turner H, Do T, Fitton D.
europepmc +1 more source
Case marking is different in monolingual and heritage Bosnian in digitally elicited oral texts. [PDF]
Jažić I, Gagarina N, Perovic A.
europepmc +1 more source
Visions of a Semantic Molecular Future [PDF]
Additional booklet insert distributed at the VSMF Symposium held at the Unilever Centre on 2011-01-17The event looks forward. Scholarship (universities, research, teaching, publishing) has been slow to take up the opportunities of this digital century ...
Murray-Rust, Peter
core

