Results 101 to 110 of about 17,254,364 (225)
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Bleating, growling, barking, and spitting: Metaphorical extensions and valency patterns of verbs of speaking. [PDF]
Brač I, Despot KŠ, Belaj B.
europepmc +1 more source
The features and factors in the acquisition of English existential constructions at the syntax-pragmatics interface by Chinese learners. [PDF]
Jiang S, Zhang H.
europepmc +1 more source
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page +4 more
wiley +1 more source
Digital solidarity and adaptation: applications developed for refugees in host countries. [PDF]
Özdemir Ö, Görgün M, Sarıoğlu EB.
europepmc +1 more source
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
Editorial: Mobilities, migration, and digital humanities. [PDF]
Chaudhuri M +6 more
europepmc +1 more source
A collection of narrative practices on cultural heritage with innovative technologies and creative strategies. [PDF]
López Salas E.
europepmc +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source

