Results 81 to 90 of about 12,400 (292)
, 2009 Our understanding of research through design is demonstrated by a close examination of the methods used in the project lifeClipper2. This design research project investigates the applicability of immersive outdoor Augmented Reality (AR).
Felix, Nadine +2 more
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
An Infrastructural Approach to Digital Ethnography: Lessons from the Manchester Infrastructures of Social Change Project [PDF]
, 2016 With the increase of digital and networked media in everyday life, researchers have increasingly turned their gaze to the symbolic and cultural elements of technologies.
Knox, HC
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
PREFIX N- AND ITS COMBINATION IN SUNDANESE: A MORPHOLOGY STUDY [PDF]
, 2017 This study analyzes the morphological process in Sundanese language, which focuses on prefix n- (nasal) and its’ combinations. This study is aimed to find the word class of the base word that can be attached by prefix n- (nasal) and its’ combination ...
Mahdi, Sutiono, Yuliyanti, Ai Yeni
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Alternate Reality Game and Culural Heritage: The “Aequilibrium” Project
Digital Studies, 2015 "Aequilibrium" is a transmedia and location-based experience which engages players in an adventure that blurs the boundaries between digital and physical spaces, imaginary and real people from the local community.
Domenico Morreale, Giulia Bertone
doaj +1 more source
Reflect – renew – refresh [PDF]
, 2018 No abstract ...
Lorimer, Hayden, Winders, Jamie
core +1 more source
A Framework For Spatial Interaction In Locative Media
, 2006 This paper presents the concepts and techniques used in afamily of location based multimedia works. The paper hasthree main sections: 1.) to describe the architecture of anaudio-visual hardware/software framework we havedeveloped for the realization of a series of locative mediaartworks, 2.) to discuss the theoretical and conceptualunderpinnings ...
Atau Tanaka, Petra Gemeinboeck
openaire +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source