Results 81 to 90 of about 1,508 (290)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Between Landscape and the Screen: Locative Media, Transitive Reading, and Environmental Storytelling

open access: yesMedia Theory, 2018
In what ways can the everyday citizen encourage sustainability and promote biodiversity in spaces that are as fragmented, industrial, and toxic as the city?
Jill Didur, Lai-Tze Fan
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

VARIABILITY OF MULTIPLE INTERPRETATIONS OF LOCATIVE-TEMPORAL CHARACTERISTICS OF A MEDIA EVENT

open access: yesВестник Кемеровского государственного университета, 2015
The article describes one of the factors influencing the interpretation of events in the media. The process of verbalization creates a cognitive model of the event, which is projected in a variety of media texts on the lexical and grammatical level ...
S. V. Mokhireva
doaj  

Alternate Reality Game and Culural Heritage: The “Aequilibrium” Project

open access: yesDigital Studies, 2015
"Aequilibrium" is a transmedia and location-based experience which engages players in an adventure that blurs the boundaries between digital and physical spaces, imaginary and real people from the local community.
Domenico Morreale, Giulia Bertone
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Modelling the Social in Locative Media: Collaborative GPS [PDF]

open access: yes, 2009
Lowry, C., Southern, J. & Speed, C. (2009) ‘Modelling the Social in Locative Media: Collaborative GPS, Second Nature Vol 1, No 2 (2009): Games, Locative & Mobile Media, RMIT University, ISSN: 1836 ...
Southern, Jen   +3 more
core   +1 more source

The Role of Hackers in Countering Surveillance and Promoting Democracy

open access: yesMedia and Communication, 2015
Practices related to media technologies and infrastructures (MTI) are an increasingly important part of democratic constellations in general and of surveillance tactics in particular. This article does not seek to discuss surveillance per se, but instead
Sebastian Kubitschko
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Psychogeography, locative media, and performativity.

open access: yes, 2008
Exploring the effective use of digital technologies to galvanise the body into political action. It discusses the interface of the virtual and the material in Ursula Biemann's video essays that mobilises the political, and considers Christian Nold's ...
Tay, S.
core  

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