Results 71 to 80 of about 1,508 (290)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Socio-spatial visualisations of cultural routes
Netcom, 2018 Cultural routes, defined as routes of historical importance that geographically represent the shared and living cultural heritage of different countries, have recently gained attention both as tourist destinations and as social repositories of collective
Catherine Emma (Kate) Jones +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Digital kinships : intergenerational locative media in Tokyo, Shanghai and Melbourne
, 2016 Drawing on three vignettes developed as short-term ethnographies (Pink and Morgan 2013) with families in Tokyo, Shanghai and Melbourne in November 2013, this chapter outlines a framework for conceptualizing the mundane ways in which locative media are ...
Horst, Heather (R20039) +8 more
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Games and science fiction. Contributing to define hybrid spaces in location-aware games
G|A|M|E The Italian Journal of Game Studies, 2012 In What Is Philosophy? (1992, p. 137) Gilles Deleuze and Félix Guattari argue that a concept is acquired by “inhabiting, by pitching one’s tent, by contracting a habit”.
Fátima Regis, Letícia Perani
doaj
A Framework For Spatial Interaction In Locative Media
, 2006 This paper presents the concepts and techniques used in afamily of location based multimedia works. The paper hasthree main sections: 1.) to describe the architecture of anaudio-visual hardware/software framework we havedeveloped for the realization of a series of locative mediaartworks, 2.) to discuss the theoretical and conceptualunderpinnings ...
Atau Tanaka, Petra Gemeinboeck
openaire +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Locative Media: From Transcendental Technologies to Socio- Formative Spheres An Examination of the Interface between Place, Agent and Locative Media [PDF]
, 2015 This thesis is a theoretical-empirical study that investigates the consequences and implications of adopting locative media technologies in everyday situations, paying particular attention to the potential strengthening of relationships between locative ...
Fazel, Maryam
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