Results 91 to 100 of about 17,254,364 (225)

Google Maps' COVID-19 layer as an interface for pandemic life. [PDF]

Mob Media Commun, 2023
Gekker A.
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Augmentative and Alternative Communication Generative Language Intervention: A Randomized Controlled Trial. [PDF]

J Speech Lang Hear Res
Binger C, Harrington N, Hahs-Vaughn DL, Kent-Walsh J.   +3 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Locative media as logistical media : situating infrastructure and the governance of labor in supply-chain capitalism

, 2015
The German-based company SAP is one of the largest developers of software that drives global economies, offering leading enterprise software solutions-specifically logistics software-that makes possible movements of people, finance, and things that ...
Rossiter, Ned (R12173)
core  

Existential priming in L2 Chinese: proficiency-selective modulation and locus-specific lexical boost. [PDF]

Front Psychol
Qian J, Cheng X, Yu J.
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

A Braille Trail for all: Inclusive design in the Karoo Desert National Botanical Garden. [PDF]

Afr J Disabil
Greyling SF, Verhoef SM, Tempelhoff WGDV.   +2 more
europepmc   +1 more source

Acquisition of L2 English spatial deixes by Arabic-speaking children. [PDF]

Front Psychol, 2022
Alothman HN, Alsager HN.
europepmc   +1 more source