Results 111 to 120 of about 1,122 (295)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A look at High Applicatives in Romanian: dative experiencers
Bucharest Working Papers in Linguistics, 2009 Romanian has both Low Applicative Phrases and High Applicative Phrases. At present, Romanian dative experiencers are High Applicatives with a dative phrase as specifier, and an (obligatory) dative clitic as head.
María Luisa Rivero
doaj
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Acquisition of Demonstratives in English and Spanish. [PDF]
Front Psychol, 2020 González-Peña P +2 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Assessing Lexical and Syntactic Comprehension in Deaf Signing Adults. [PDF]
J Deaf Stud Deaf Educ, 2023 Zorzi G +5 more
europepmc +1 more source
A Corpus-based Description of Locative and Non-locative Reference in Kirundi Locative Enclitics
Africana Linguistica, 2017 Devos, Maud +2 more
openaire +2 more sources
The Semantics of Locatives in the Uralic Languages
, 2005 Kracht M. The Semantics of Locatives in the Uralic Languages. In: Fernandez-Vest J, ed. Les languages ouraliennes aujourd'hui. Approche linguistics et cognitive. Bibilothèque de l'Ecole des Hautes Etudes, Sciences Historiques et Philologiques.
Kracht, Marcus, Fernandez-Vest, Jocelyne
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source