Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Étude de faisabilité du dispositif « Passerelle » couplant transfert monétaire non fléché et orientation sociale destiné à des ménages en situation de précarité en France. [PDF]
Gallinari-Safar P +11 more
europepmc +1 more source
Do Children with SLI Use Verbs to Predict Arguments and Adjuncts: Evidence from Eye Movements During Listening. [PDF]
Andreu L +2 more
europepmc +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Putting the prime in priming: Using prime processing behavior to predict target structural processing. [PDF]
Tooley KM, Brehm L.
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Mapping Concepts Onto Linguistic Structure: The Case of Animacy. [PDF]
Fukumura K.
europepmc +1 more source
Early Sentence Productions of 3- and 4-Year-Old Children Who Use Augmentative and Alternative Communication. [PDF]
Binger C +3 more
europepmc +1 more source
Simultaneous structures in sign languages: Acquisition and emergence. [PDF]
Loos C, German A, Meier RP.
europepmc +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source

