Results 191 to 200 of about 102,027 (262)

Intracortical Injection of Okadaic Acid Increases Locomotor Activity and Decreases Anxiety-like Behaviour in Adult Male Rats: Potential Involvement of NMDA Receptor. [PDF]

Ann Neurosci
Jacob RS, Gunasekaran S, Kumar M, Omkumar RV.   +3 more
europepmc   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Adipocyte‐Derived Exosomal miR‐5099 Mitigates M1 Macrophage Polarization and Adipose Inflammation via c‐Met/NF‐κB Axis to Improve Metabolic Health

Advanced Science, EarlyView.
Celastrol upregulates adipocyte‐derived exosomal miR‐5099, suppressing the macrophage c‐Met/NF‐κB axis to mitigate pro‐inflammatory M1 polarization and adipose inflammation. These miR‐5099‐enriched exosomes also act as endocrine signals targeting the liver, muscle, and adipocytes to significantly enhance systemic insulin sensitivity.
Ping Tang, Lixin Tai, Hongxia Xu, Dongliang Zhu, Jiajia Li, Hao Feng, Jinghui Cui, Shuhai Lin, Li‐jun Di, Li Wang   +9 more
wiley   +1 more source

Selection for greater dispersal in early life increases rate of age-dependent decline in locomotor activity and shortens lifespan. [PDF]

J Evol Biol
Ruchitha BG, Kumar N, Sura C, Tung S.
europepmc   +1 more source

High vector competence for chikungunya virus but heavily reduced locomotor activity of Aedes albopictus from Germany at low temperatures. [PDF]

Parasit Vectors
Lühken R, Rauhöft L, Pluskota B, Lange U, Helms M, Becker N, Schmidt-Chanasit J, Kuhn C, Tannich E, Jansen S, Heitmann A.   +10 more
europepmc   +1 more source

A novel small-animal locomotor activity recording device for biological clock research. [PDF]

Animal Model Exp Med
Wu YL, Zhong M, Yin J, Ou WJ, Zhuang YB, Zhang NW, Lin S, Zhu YY.   +7 more
europepmc   +1 more source

Parental Serotonin Modulation Alters Monoamine Balance in Identified Neurons and Affects Locomotor Activity in Progeny of <i>Lymnaea stagnalis</i> (Mollusca: Gastropoda). [PDF]

Int J Mol Sci
Shestipalova A, Nikishchenko V, Bogomolov A, Voronezhskaya EE.   +3 more
europepmc   +1 more source

Effects of repeated voluntary oral consumption of synthetic delta-9-tetrahydrocannabinol on locomotor activity and cannabinoid receptor 1 expression. [PDF]

Behav Brain Res
Laux DA, Azuma MC, Cain ME.
europepmc   +1 more source

Influence of feeding time on daily rhythms of locomotor activity, clock genes, and epigenetic mechanisms in the liver and hypothalamus of the European sea bass (Dicentrarchus labrax). [PDF]

Fish Physiol Biochem
Samorì E, Rodríguez I, Oliver JA, Sánchez-Vázquez FJ, López-Olmeda JF.   +4 more
europepmc   +1 more source