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Hyperoxia and Locomotor Activity in Rats
Perceptual and Motor Skills, 1968Exposure to an 8% O2 atmosphere (hypoxia) reduced activity-wheel running of rats approximately 50% with respect to a 21% O2 (normoxia) control condition. Exposure to 30, 60, and 100% O2 (hyperoxia) did not affect locomotor activity.
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Effect of Strychnine Sulfate on Locomotor Activity
Perceptual and Motor Skills, 1965The effect of strychnine sulfate upon spontaneous locomotor activity in an open field was determined for 20 naive male Wistar rats. The experimental Ss were injected ip with 1.0 cc/kg of a 01% solution of strychnine sulfate in normal saline and the control Ss received a similar injection of 1.0 cc/kg of normal saline. All Ss were given 2 trials 7 days
R G, GIBBY +3 more
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MDMA produces stimulant-like conditioned locomotor activity
Psychopharmacology, 1989Daily administration of a drug in a distinctive environment establishes contingencies that support Pavlovian conditioning. Environmental cues that are paired with the drug injection and that predict the onset of drug action can become conditioned stimuli.
L H, Gold, G F, Koob
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Cerebral ischemia, locomotor activity and spatial mapping
Brain Research, 1990A 5-min bilateral occlusion of the carotid arteries produced large increases in gerbil locomotor activity that persisted for a week of daily testing after the ischemic episode. In a second group of animals, 5 days of pre-exposure to the open-field prior to inducing ischemia blocked the development of increased locomotor activation.
D, Wang, D, Corbett
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Monoamine synthesis and caffeine-induced locomotor activity
Neuropharmacology, 1978Abstract Alpha-methyltyrosine and para-chlorophenylalanine were used to investigate the effect of inhibition of catecholamine and serotonin synthesis, respectively, on caffeine-induced activity. Alphamethyltyrosine prevented caffeine-induced activity which was substantially restored by apparent replacement of catecholamine synthesis by l -Dopa ...
B C, White +3 more
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Locomotor activity and exploration
1993Publisher Summary This chapter provides an overview of locomotor activity and exploration. The analysis of the drug effects on general motor activity and exploratory behavior has been central to the field of behavioral pharmacology since its inception.
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Hyperuricemia and locomotor activity in developing rats
Pharmacology Biochemistry and Behavior, 1989This research was motivated by the previous finding that serum uric acid levels correlate with symptoms of hyperactivity in normal children. We attempted, therefore, to investigate this relationship in an animal model. Dose and time relationships between allantoxanamide-induced heightened serum uric acid and locomotor activity were investigated. A dose-
C M, Barrera, R E, Hunter, W P, Dunlap
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Individual differences in locomotor activity and sensitization
Pharmacology Biochemistry and Behavior, 1991Male rats were screened for locomotor activity in a novel environment and divided into high (HR) and low (LR) responders based on whether their locomotor activity score for the first hour was above or below the median locomotor activity for the subject sample.
M S, Hooks +4 more
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Circadian Rhythms of Locomotor Activity in Zebrafish
Physiology & Behavior, 1998As part of an effort to characterize the circadian system of the zebrafish, we examined the circadian regulation of locomotor activity in adult males and females. Gross locomotor activity was measured using infrared movement detectors. The effects of light, dark, and temperature on the amplitude, phase, and free-running periods of locomotor rhythms ...
M W, Hurd +3 more
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Circadian rhythms of locomotor activity in Drosophila
Behavioural Processes, 2003Drosophila is by far the most advanced model to understand the complex biochemical interactions upon which circadian clocks rely. Most of the genes that have been characterized so far were isolated through genetic screens using the locomotor activity rhythms of the adults as a circadian output.
Klarsfeld, André +2 more
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