Results 231 to 240 of about 5,915,980 (298)

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

Advanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang, Siru Zhou, Xi Liu, Wei Xiang, Xiuqin Peng, Yu Tian, Song Li, Hailin Wang, Bo Liao, Shunzheng Fang, Runze Jin, Jinhui Wu, Chuanqing Bai, Wei Zhang, Bo Huang, Bingfei Li, Lifeng Chen, Lin Chen, Bin Zhang, Zhenhong Ni   +19 more
wiley   +1 more source

The reduction in locomotor activity induced by restraint stress in young male mice involves the downregulation of hippocampal serotonergic and dopaminergic markers. [PDF]

IBRO Neurosci Rep
Furukawa M, Izumo N, Toho M, Aoki R, Nishijima H, Nakamura Y, Sakai Y, Ishibashi Y, Kurono H, Manabe T, Matsuzaki H.   +10 more
europepmc   +1 more source

Emergent Spinning and Orbital Motion in Clustered Wind‐Assisted Flyers

Advanced Science, EarlyView.
Inspired by natural snowflake geometries, paper‐cut flyers exhibit geometry‐defined spinning and orbital motions during cluster formation in a wind tunnel. Collective flights of multiple paperflakes reveal dynamic clustering, fragmentation, and continuously evolving spin behaviors.
Bingnan Zhou, Rahul Chand, Fahad Ahmed Korai, Jianfeng Yang, Valtteri Savonen, Fan Liu, Qi Yang, Hao Zeng   +7 more
wiley   +1 more source

Small mosquitoes: large implications-effects of larval crowding and starvation on locomotor activity, adult biting frequency, and insecticide resistance in two strains of Aedes aegypti. [PDF]

Parasit Vectors
Karki A, Luker HA, Salas KR, Hansen IA.
europepmc   +1 more source

Pilot Study: Simultaneous Daily Recording of Total Locomotor Activity and Heart Rate in Horses for Application in Precision Livestock Farming. [PDF]

Animals (Basel)
Aragona F, Rizzo M, Arrigo F, Arfuso F, Fazio F, Giudice E, Pugliatti P, Piccione G, Giannetto C.   +8 more
europepmc   +1 more source

Orchiectomy Decreases Locomotor Activity and Delays the Expression of the Clock Protein PER1 in the Suprachiasmatic Nucleus in Rabbits. [PDF]

Animals (Basel)
Guzmán-Acevedo ÁR, Caba-Flores MD, Viveros-Contreras R, Meza-Alvarado JE.   +3 more
europepmc   +1 more source

Locomotor Activity Monitoring in Mice to Study the Phase Shift of Circadian Rhythms Using ClockLab (Actimetrics). [PDF]

Bio Protoc
Brenna A, Ripperger JA, Albrecht U.
europepmc   +1 more source

Administration of Bisphosphonate Preparations to Mice with Mild-type Hypophosphatasia Reduces the Quality of Spontaneous Locomotor Activity. [PDF]

Calcif Tissue Int
Nakamura-Takahashi A, Ishizuka S, Hirai K, Matsunaga S, Kasahara N, Shintani S, Abe S, Kasahara M.   +7 more
europepmc   +1 more source

Detection of aberrant locomotor activity in a mouse model of lung cancer via home cage monitoring. [PDF]

Front Oncol
Tomanelli M, Guffanti F, Vargiu G, Micotti E, Rigamonti M, Tumiatti F, Caiola E, Marabese M, Broggini M.   +8 more
europepmc   +1 more source