Results 101 to 110 of about 57,725 (204)

Radical‐Mediated In Situ Fluorescence Dye Deposition: A Simple Interfacial Signal Amplification Reaction for Ultrasensitive Immunoassay on Barcode Beads

open access: yesAdvanced Science, EarlyView.
A radical‐mediated in situ fluorescence dye deposition (RIFD) reaction containing merely three elements of beads, dyes, and radicals is discovered for the first time, and its underlying mechanism is elucidated. This simple RIFD enables the interfacial and ultrafast deposition of free dyes onto barcode beads, serving as a powerful signal amplification ...
Jiayu Zhang   +8 more
wiley   +1 more source

A Novel Hybrid Approach for UT1-UTC Ultra-Short-Term Prediction Utilizing LOD Series and Sum Series of LOD and First-Order-Difference UT1-UTC

open access: yesSensors
Accurate ultra-short-term prediction of UT1-UTC is crucial for real-time applications in high-precision reference frame conversions. Presently, traditional LS + AR and LS + MAR hybrid methods are commonly employed for UT1-UTC prediction.
Fei Ye   +4 more
doaj   +1 more source

Removing Regional Trends in Microgravity in Complex Environments: Testing on 3D Model and Field Investigations in the Eastern Dead Sea Coast (Jordan)

open access: yesInternational Journal of Geophysics, 2013
Microgravity investigations are now recognized as a powerful tool for subsurface imaging and especially for the localization of underground karsts. However numerous natural (geological), technical, and environmental factors interfere with microgravity ...
A. Al-Zoubi   +4 more
doaj   +1 more source

Pragmatic Use of LOD - a Modular Approach [PDF]

open access: yes, 2016
The concept of Level of Development (LOD) is a simple approach to specifying the requirements for the content of object-oriented models in a Building Information Modelling process.
Treldal, Niels   +2 more
core  

High‐Density E. Coli Cultivation Arrays for Combinatorial Drug Testing With Subsequent Lipid Profiling by MALDI‐MS

open access: yesAdvanced Science, EarlyView.
High‐throughput antibiotic cross‐gradient assays on microdroplet arrays. A multichannel printhead together with five pressure regulators forms droplet arrays of up to 20 832 droplets within 25 minutes. Each droplet contains unique concentrations of antibiotics, allowing to moniture a vast spectrum of bacterial repsonses over night. The bacterial growth
M. Breitfeld   +5 more
wiley   +1 more source

Synchronized Imaging of Hydrogen Peroxide and Hydroxyl Radical in Pyroptosis and Epilepsy

open access: yesAdvanced Science, EarlyView.
A dual‐responsive fluorescent probe, HH, enables synchronized visualization of H2O2 and •OH through spectrally resolved green and red channels. By tracking redox dynamics in pyroptosis and epilepsy models, HH reveals ROS elevation during seizure‐like pathology and supports evaluation of antioxidant and antiepileptic therapeutic interventions.
Yabing Gan   +9 more
wiley   +1 more source

Biomimetic Nucleus Pulposus Replacement for the Treatment of Degenerative Disc Disease

open access: yesGlobal Spine Journal, 2015
Introduction Nucleus pulposus (NP) replacement offers an alternative minimally invasive treatment for traditional spinal fusion or total disc replacement for degenerative disc disease (DDD).
Gernot Lang   +7 more
doaj   +1 more source

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

open access: yesAdvanced Science, EarlyView.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang   +20 more
wiley   +1 more source

Ligation overcomes terminal underrepresentation in multiple displacement amplification of linear DNA

open access: yesBioTechniques, 2005
Simona Panelli   +3 more
doaj   +1 more source

Single‐Atom‐Enhanced Fully Inkjet‐Printed Electrochemical Sensor for Dopamine Detection

open access: yesAdvanced Science, EarlyView.
Fully inkjet‐printed paper‐based dopamine sensors are fabricated using nitrogen‐doped graphene acid functionalized with copper single atoms. The copper sites uniquely enhance dopamine oxidation through strong molecular adsorption, as verified by electrochemical measurements and DFT calculations. The approach highlights the potential of single‐atom inks
Martin‐Alex Nalepa   +11 more
wiley   +1 more source

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