Results 131 to 140 of about 177,969 (300)

LOD curve graph of four growth-related QTLs.

open access: yes, 2012
Abscissa indicates the relative position on the linkage groups, vertical coordinates indicates the value of LOD; the figure in “()” represents (position, value of LOD).
Yongwei Zhao (109388)   +10 more
core   +1 more source

CRISPR‐Scan: Cas13a Mismatch Tolerance Enabled Ultra‐Multiplexed Detection of Same‐Site Indels in Acute Myeloid Leukemia

open access: yesAdvanced Science, EarlyView.
Accurately detecting diverse same‐locus insertions or deletions (indels) remains challenging. This study reveals the mismatch‐tolerance profile of LwaCas13a and establishes CRISPR‐Scan, which uses a single crRNA to detect multiple same‐locus indels. The one‐pot assay detects nucleophosmin 1 (NPM1) mutant allele frequencies down to 0.01%, agrees with ...
Linlin Bai   +13 more
wiley   +1 more source

LOD distributions on the iPad.

open access: yes, 2015
LOD distributions on the iPad.
Siyuan Liu (696701)   +4 more
core   +1 more source

Scaffold RNA Reengineering for a Leakage‐Suppressed CRISPR/Cas12a Cascade System Toward Precise Nucleic Acid Diagnostics

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the CALCas system, in which a conformational switch in the 3' terminal DNA extension of scaffold RNA (3'D‐SR) drives cascade‐activatable Cas12a cleavage while suppressing leakage. ABSTRACT Amplification‐free CRISPR detection has attracted significant attention for its capacity to circumvent the intricacies of nucleic acid ...
Xingrong Li   +11 more
wiley   +1 more source

Ravulizumab in adults and children with atypical hemolytic uremic syndrome: a plain language summary of three studies

open access: yesJournal of Comparative Effectiveness Research
This summary gives an overview of three published articles that report the results of research studies of ravulizumab, an approved treatment for people with atypical hemolytic uremic syndrome (often shortened to aHUS).
Michal Nowicki, Nikoleta Printza
doaj   +1 more source

Effects of risk factors on the development and mortality of early- and late-onset dementia: an 11-year longitudinal nationwide population-based cohort study in South Korea

open access: yesAlzheimer’s Research & Therapy
Background Early-onset dementia (EOD, onset age 
Min Young Chun   +11 more
doaj   +1 more source

Sub‐Second Ratiometric Fluorescence Imaging of Histamine Dynamics in Living Cells via a Supramolecular Probe

open access: yesAdvanced Science, EarlyView.
A tailored tripartite supramolecular ratiometric probe, engineered by modulating the fluorogenic guest's cationic locus, enables ultrafast histamine monitoring in living cells. Utilizing a competitive displacement mechanism, this system achieves a sub‐second response time with high selectivity.
Chenming Chan   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy