Results 131 to 140 of about 28,496 (267)

Revisions to the <i>Gliophorus irrigatus</i> complex (Agaricales, Hygrophoraceae, <i>Gliophorus</i>, section Unguinosae) including four new species, one new combination and comparisons of basidiome vs. eDNA distributions. [PDF]

MycoKeys
Harries DJ, Blencowe CM, Leal-Dutra CA, Lodge DJ, Harrington AH, Bye R, Pearse Z, Russell SD, Williams J, Ré LA, Griffith GW.   +10 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Activation of 5-HT4 receptors reverses stress-induced dopamine system dysregulation. [PDF]

Neuropharmacology
Yang OJ, Perez SM, Lodge DJ.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Acetylation and accessibility of <i>Cryptococcus neoformans</i> cell wall chitosans influence the strength of host immune responses. [PDF]

Cell Surf
Hellmann MJ, Upadhya R, Tchoub E, Moerschbacher BM, Lodge JK, Cord-Landwehr S.   +5 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Pathogen screening of Zambian ticks: new insights on the occurrence of tick-borne pathogens in the country. [PDF]

Parasit Vectors
Makayi C, Simainga S, Mertens-Scholz K, Chitimia-Dobler L, Fischer S, Labruna MB, Mans BJ, Dautu G, Brangsch H, Simuunza M, Groschup MH, Schulz A.   +11 more
europepmc   +1 more source

The Lodge, Clare

, 2018
Inspection date: 11/07 ...
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Sporecasting Biogeography Across Scales: Continental Patterns and Local Constraints on Macrofungal Dispersal. [PDF]

Mol Ecol
Ratz AW, Arnold AE, Burrill HM, Caiafa MV, Conery J, Dawson HA, Delevich CA, Diez JM, Frey SD, Lodge DJ, Ronold EK, Roy BA, Smith ME, U'Ren J, Wilson AW, Loucks JJ, Wuest J, Willis CB, Kennedy PG.   +18 more
europepmc   +1 more source