Results 141 to 150 of about 130,902 (295)

Pertumbuhan dan Produksi Rumput Odot (Pennisetum purpureum cv. Mott) pada Tanah Entisol di Lahan Kering Akibat Pemberian Pupuk Organik Cair Berbahan Feses Babi Dengan Volume Air Berbeda

Jurnal Ilmu Peternakan Terapan, 2019
This study aims to examine the growth and production of odot grass (Pennisetum purpureum cv. Mott) on entisol soils with different amounts of water volume in Liquid Organic Fertilizer (LOF) made of pig feces.
Celeste De Araujo, Maria Yasinta Un, Bernadete Barek Koten, Melkianus D. S. Randu, Redempta Wea   +4 more
doaj  

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies.
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, Volume 158, Issue 6, Page 1617-1627, 15 March 2026.
What's new? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source

Morphometric characteristics and their influence on soil hydrological properties in Kiltie watershed, Upper Blue Nile Basin, Ethiopia

Agrosystems, Geosciences &Environment, Volume 9, Issue 1, March 2026.
Abstract Morphometric analysis is crucial for watershed management, especially for estimating infiltration rate and erosion characteristics. However, there is limited research on the relationship between morphometric characteristics and soil hydrological properties in the Kiltie watershed.
Getu Abey Denekewu, Derege Tsegaye Meshesha, Enyew Adgo Tsegaye   +2 more
wiley   +1 more source

Powerful Foldover Designs

Quality and Reliability Engineering International, Volume 42, Issue 2, Page 553-564, March 2026.
ABSTRACT The foldover technique for screening designs is well‐known to guarantee zero aliasing of the main effect estimators with respect to two‐factor interactions and quadratic effects. It is a key feature of many popular response surface designs, including central composite designs, definitive screening designs, and most orthogonal, minimally ...
Jonathan Stallrich, Rakhi Singh, Kyle Vogt‐Lowell, Fanxing Li   +3 more
wiley   +1 more source

‌Rockburst intensity grading prediction based on the LOF-ENN-KNN model‌

Scientific Reports
Rockburst is a typical dynamic disaster in deep underground engineering, and its accurate prediction is of great significance to ensure the safety of engineering.
Haoran Ge, Jiyong Zhang, Congbo Ma, Kai Hui, Yicong Li, Ziniu Wu   +5 more
doaj   +1 more source

Critical Review for One‐Class Classification: Recent Advances and Reality Behind Them

WIREs Data Mining and Knowledge Discovery, Volume 16, Issue 1, March 2026.
This review presents a new taxonomy to summarize one‐class classification (OCC) algorithms and their applications. The main argument is that OCC should not learn multiple classes. The paper highlights common violations of OCC involving multiple classes.
Toshitaka Hayashi, Dalibor Cimr, Hamido Fujita, Richard Cimler   +3 more
wiley   +1 more source

Exploring Persistent Apical Periodontitis in Humans: Integrative Genetic, Histological and Microbiological Perspectives for Translational Research

International Endodontic Journal, Volume 59, Issue 3, Page 486-501, March 2026.
ABSTRACT Aim To evaluate the impact of polymorphisms in SOCS‐1, TNF‐α and RANKL on gene expression of RANK, RANKL, TNFRSF1, SOCS‐1, IL‐10, IL‐1β and TNF‐α, and to evaluate the histopathological, immunohistochemical and microbiological aspects of persistent apical periodontitis (PAP) after root canal treatment (RCT) in Brazilian individuals ...
Igor Bassi Ferreira Petean, Alice Corrêa Silva‐Sousa, Rafael Verardino de Camargo, Yara Terezinha Corrêa Silva‐Sousa, Fernanda Gonçalves Basso, André Pitondo‐Silva, Francisco Wanderley Garcia de Paula‐Silva, Erika Calvano Kuchler, Raquel Assed Bezerra da Silva, Lea Assed Bezerra da Silva, Jardel Francisco Mazzi‐Chaves, Fabiane Carneiro Lopes‐Olhê, Manoel Damião Sousa‐Neto   +12 more
wiley   +1 more source

Oncogenic NRAS Mutation in Incipient Sarcomatous Transformation of Cystic Nephroma From a Patient With DICER1‐Related Tumor Predisposition Syndrome

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Anaplastic sarcoma of the kidney (ASK) is a DICER1‐associated malignant tumor presumed to arise in a benign precursor, pediatric cystic nephroma (PCN). However, the initial oncogenic alteration(s) associated with malignant transformation are unknown.
Nahir Cortes‐Santiago, Sarah B. Whittle, Sarah Scollon, Sharon E. Plon, Sanjeev Vasudevan, Bryony J. Lucas, Angshumoy Roy   +6 more
wiley   +1 more source

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, Volume 13, Issue 9, 13 February 2026.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source