Results 61 to 70 of about 396,841 (260)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

The predictors of treatment adherence among hypertensive patients with cost-free access

Scientific Reports
The level and predictors of medication adherence have not been given attention among populations for whom the cost of treatment is not a concern, especially in the Ghanaian healthcare setting.
Felix Kwasi Nyande, Kennedy Diema Konlan, Linda Serwaa Asiamah, Vivian Boateng, Joyce Gbeamir, Veronica Dankwah, Robert Quaicoe, David Adedia   +7 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Regularized log-linear models for predicting underwater radiated noise spectra of small vessels

Frontiers in Marine Science
Underwater radiated noise (URN) from vessels is an anthropogenic stressor that negatively affects marine ecosystems. Accordingly, the ability to estimate URN levels is a critical component for environmental assessment.
Mark Shipton, Roee Diamant, Roee Diamant
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Spatio-Temporal Count Autoregression

Data Science in Science
We study the problem of modeling and inference for spatio-temporal count processes. Our approach uses parsimonious parameterisations of multivariate autoregressive count time series models, including possible regression on covariates.
Steffen Maletz, Konstantinos Fokianos, Roland Fried   +2 more
doaj   +1 more source

COMPOSITE MIXTURE OF LOG-LINEAR MODELS WITH APPLICATION TO PSYCHIATRIC STUDIES. [PDF]

Ann Appl Stat, 2022
Aliverti E, Dunson DB.
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

PENENTUAN BENTUK FUNGSI MODEL EMPIRIK: STUDI KASUS PERMINTAAN KENDARAAN RODA EMPAT BARU

JEJAK: Jurnal Ekonomi dan Kebijakan, 2012
In many cases, the determination of form of the regression function of the empirical model betweenthe linear model and the log-linear model is neglected when someone starts research.
Andryan Setyadharma
doaj   +1 more source

Analytical results for directional and quadratic selection gradients for log-linear models of fitness functions. [PDF]

Evolution, 2022
Morrissey MB, Goudie IBJ.
europepmc   +1 more source