Results 81 to 90 of about 397,901 (297)
Analytical results for directional and quadratic selection gradients for log-linear models of fitness functions. [PDF]
Evolution, 2022 Morrissey MB, Goudie IBJ.
europepmc +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Algebraic Methods for Log-Linear Models
, 2012 Techniques from representation theory (Diaconis, 1988) and algebraic geometry (Drton et al., 2008) have been applied to the statistical analysis of discrete data with log-linear models.
Pribadi, Aaron, Aaron Pribadi
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Analysis of test results via log-linear models
, 1981 The recently developed log-linear model procedures are applied to three types of data arising in a measurement context. First, because of the historical intersection of survey methods and test norming, the log-linear model approach should have ...
Baker, Frank B., Subkoviak, Michael J.
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FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Monitoring Multinomial Logit Profiles via Log-Linear Models (Quality Engineering Conference Paper)
International Journal of Industrial Engineering and Production Research, 2013 In certain statistical process control applications, quality of a process or product can be characterized by a function commonly referred to as profile.
Rassoul Noorossana +3 more
doaj
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Efficient comparison of independence structures of log-linear models
, 2022 Log-linear models are a family of probability distributions which capture relationships between variables. They have been proven useful in a wide variety of fields such as epidemiology, economics and sociology.
Bromberg, Facundo, Strappa, Jan
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FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source