Results 31 to 40 of about 425,892 (298)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
LQ-Moments: Application to the Log-Normal distribution [PDF]
Journal of Mathematics and Statistics, 2006 Summary: \textit{G. S. Mudolkar} and \textit{A. D. Hutson} [J. Stat. Plann. Inference 71, No.~1--2, 191--208 (1998; Zbl 0981.62039)] extended L-moments to new moments called LQ-moments (LQMOM). The LQMOM are constructed by using functionals defining quick estimators, where the parameters of quick estimators take the values \(p = 0\), \(\alpha = 1\) for
Shabri, Ani, Jemain, Abdul Aziz
openaire +2 more sources
Mechanisms for log normal concentration distributions in the environment [PDF]
Scientific Reports, 2021 AbstractLog normal-like concentration distributions are ubiquitously observed in the environment. However, the mechanistic origins are not well understood. In this paper, we show that first order exponential kinetics onsets log-normal concentration distributions, under certain assumptions.
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Distribution of linear functions from ordered bivariate log-normal distribution [PDF]
, 2012 In this work we consider the problem of finding the distribution of linear functions of the minimum and the maximum of the bivariate log-normal distribution. We derive the distribution function, density function and moments of these statistics. This work
Genc, Ali I.
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Frontiers in Environmental Science, 2022 In developing wastewater treatment regulations and guidelines for potable reuse, the reduction of pathogens is of critical importance. In draft regulations, the state of California has proposed overall treatment process log reduction values (LRVs) of 20,
George Tchobanoglous +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Discriminating between the Weibull and log‐normal distributions [PDF]
Naval Research Logistics (NRL), 2004 AbstractLog‐normal and Weibull distributions are the most popular distributions for modeling skewed data. In this paper, we consider the ratio of the maximized likelihood in choosing between the two distributions. The asymptotic distribution of the logarithm of the maximized likelihood ratio has been obtained.
Kundu, Debasis, Manglick, Anubhav
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Parameters of log-normal distribution in simulation.
, 2019 Parameters of log-normal distribution in simulation.
Zhao-Fa Liu (6990056) +5 more
core +1 more source