Results 41 to 50 of about 425,892 (298)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Comparison Between Different Probability Distributions for Modeling Exchange Rate Volatility Behavior in Oil Countries for the Period 1990 – 2022

Wasit Journal for Pure Sciences
this study examines the distributional properties of exchange rate volatility for major oil-exporting developing economies from 1990-2022. Three probability distributions [ Normal, Fr'echet, and Log Normal] are compared using moment method and maximum ...
Awatif Al-Dubaicy
doaj   +1 more source

Rainfall probability modeling for Neelambur areas of Coimbatore, Tamil Nadu

Journal of Agrometeorology, 2009
Daily rainfall data obtained from the rain gauge station, Sulur (110 N and 770 E) were analyzed for fitting one day maximum rainfall, average weekly, monthly and seasonal rainfall data, using different distributions like Normal, Log-normal, Gumbel and ...
B. MAHESHWARA BABU, D. C. SAHOO
doaj   +1 more source

Copulas for statistical signal processing (Part I) : extensions and generalization

, 2014
Existing works on multivariate distributions mainly focus on limited distribution functions and require that the associated marginal distributions belong to the same family. Although this simplifies problems, it may fail to deal with practical cases when
Wang, Zheng, Zeng, Xuexing, Ren, Jinchang, Marshall, Stephen, Durrani, Tariq   +4 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Mixed Size-Biased Log-Normal Distribution with Truncated Normal Prior and Its Application in Insurance Ratemaking

Risks
In the insurance literature, accurately predicting extreme losses has been a persistent and important problem. Recently, under the modelling framework of weighted distributions, several finite-mixture size-biased distributions, including size-biased ...
Taehan Bae, Jieun Kim, Jae Youn Ahn
doaj   +1 more source

Particle size and its distribution deduced from magnetic properties of magnetite nanoparticles by the modified Langevin equation

AIP Advances, 2023
The magnetic hysteresis curve can provide information about magnetic properties, particle size, and its distribution. For superparamagnetic materials, the characteristics of the hysteresis curve are very typical, that is, Hc is equal to zero with a ...
Togar Saragi, Utami Widyaiswari, Darling Josua Manalu, Budi Adiperdana, Risdiana Risdiana, Tadashi Adachi   +5 more
doaj   +1 more source

The Use of a Log-Normal Prior for the Student t-Distribution

Axioms, 2022
It is typically difficult to estimate the number of degrees of freedom due to the leptokurtic nature of the Student t-distribution. Particularly in studies with small sample sizes, special care is needed concerning prior choice in order to ensure that ...
Se Yoon Lee
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

High Reproducibility of ELISPOT Counts from Nine Different Laboratories

Cells, 2015
The primary goal of immune monitoring with ELISPOT is to measure the number of T cells, specific for any antigen, accurately and reproducibly between different laboratories.
Srividya Sundararaman, Alexey Y. Karulin, Tameem Ansari, Nadine BenHamouda, Judith Gottwein, Sreenivas Laxmanan, Steven M. Levine, John T. Loffredo, Stephanie McArdle, Christine Neudoerfl, Diana Roen, Karina Silina, Mackenzie Welch, Paul V. Lehmann   +13 more
doaj   +1 more source