Log P Determines Licorice Flavonoids Release Behaviors and Classification from CARBOMER Cross-Linked Hydrogel [PDF]
The dynamic drug release mechanisms from Carbomer 940 (CP) hydrogels have not been systematically explored elsewhere. This study aimed to investigate the quantitative structure−activity relationship of licorice flavonoids (LFs) compounds on their drug ...
Zhuxian Wang +12 more
doaj +2 more sources
Evaluation of log P, pKa, and log D predictions from the SAMPL7 blind challenge. [PDF]
Abstract The Statistical Assessment of Modeling of Proteins and Ligands (SAMPL) challenges focuses the computational modeling community on areas in need of improvement for rational drug design. The SAMPL7 physical property challenge dealt with prediction of octanol-water partition coefficients and p
Bergazin TD +8 more
europepmc +7 more sources
Physical Computation, P/poly and P/log* [PDF]
In this paper we give a framework for describing how abstract systems can be used to compute if no randomness or error is involved. Using this we describe a class of classical "physical" computation systems whose computational capabilities in polynomial ...
Richard Whyman
doaj +4 more sources
Normality of the p-Harmonic and Log-p-Harmonic Mappings [PDF]
In this paper, the concepts of p-harmonic mappings and log-p-harmonic mappings in the unit disk have been introduced and studied by many researchers. We proved the normality of the p-harmonic mappings and log-p-harmonic mappings, which extend the related
Qinghua Jiang +2 more
doaj +2 more sources
A systems approach using OSMAC, Log P and NMR fingerprinting: An approach to novelty [PDF]
The growing number of sequenced microbial genomes has revealed a remarkably large number of secondary metabolite biosynthetic clusters for which the compounds are still unknown.
Miaomiao Liu +5 more
doaj +2 more sources
Log-concavity of P-recursive sequences [PDF]
We consider the higher order Turán inequality and higher order log-concavity for sequences $\{a_n\}_{n \ge 0}$ such that \[ \frac{a_{n-1}a_{n+1}}{a_n^2} = 1 + \sum_{i=1}^m \frac{r_i(\log n)}{n^{α_i}} + o\left( \frac{1}{n^β} \right), \] where $m$ is a nonnegative integer, $α_i$ are real numbers, $r_i(x)$ are rational functions of $x$ and \[ 0 < α_1 ...
Hou, Qing-hu, Li, Guojie
openaire +2 more sources
Log p-divisible groups associated with log 1-motives
AbstractWe first provide a detailed proof of Kato’s classification theorem of log p-divisible groups over a Noetherian Henselian local ring. Exploring Kato’s idea further, we then define the notion of a standard extension of a classical finite étale group scheme (resp.
Matti Würthen, Heer Zhao
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Multiscaling and joint multiscaling description of the atmospheric wind speed and the aggregate power output from a wind farm [PDF]
We consider here wind speed time series and the aggregate output wind power from a wind farm. We study their scaling statistics in the framework of fully developed turbulence and Kolmogorov's theory.
R. Calif, F. G. Schmitt
doaj +1 more source
Intravenous lipid emulsion for the treatment of poisonings in 313 dogs and 100 cats (2016–2020)
IntroductionThe aim of this retrospective study was to analyze the effect and potential adverse effects of intravenous lipid emulsion (ILE) in poisoned dogs and cats over a 5 years period.MethodsMedical records of 313 dogs and 100 cats receiving ILE ...
Carina Markert +4 more
doaj +1 more source
“Click” synthesis of amphiphilic carbohydrate-alkyl triazole derivatives
1,4-disubstituted 1H-1,2,3-triazole with a hydrophobic and hydrophilic moiety were synthesized by using Cu(I) catalyzed alkyne-azide 1,3-dipolar cycloaddition reaction.
Mario Daniel Contin +2 more
doaj +1 more source

