Results 91 to 100 of about 44,276 (294)

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

Three-Dimensional Parameterization of Submesoscale Eddy From HiSea-II Imagery

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
The detection of submesoscale eddies is limited by altimeter resolution and the complex dynamics of eddy formation and dissipation, resulting in an incomplete understanding of their structure.
Linyao Ge, Ge Chen, Daosheng Wang, Xiaoyan Chen, Zhongping Lee, Baoxiang Huang   +5 more
doaj   +1 more source

Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts

Advanced Science, EarlyView.
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang, Jiaming Sun, Ying Wang, Bichen Ren, Yuxin Liu, Yunhan Liu, Liang Chen, Lu Yu, Tao Dai, Li Yu, Zhihui Dong   +10 more
wiley   +1 more source

Numerical investigation of coarse granular flow of the Coandă effect-based collector over logarithmic spiral surface for deepsea mining

Applied Ocean Research
As an emerging hydraulic harvester for deep-ocean polymetallic nodules, Coandă effect-based collectors aim to minimize seabed disturbance while maintaining high collector efficiency.
Hao Jia, Ya-peng Wang, Jian Yang
doaj   +1 more source

DESIGN AND OPTIMISATION OF TEETH FOR THE 5TD-1200 SOYBEAN THRESHER [PDF]

Engenharia Agrícola
Drum speed is a key parameter controlling threshing intensity: excessively high speeds cause a high proportion of broken grains (due to uneven impact), while excessively low speeds leave more unthreshed grains.
Yujiao Teng, Mengran Cui, Shunchang Guo, Bendi Qi, Xin Feng   +4 more
doaj   +1 more source

Three-Dimensional Distribution of the ISM in the Milky Way Galaxy: III. The Total Neutral Gas Disk

, 2015
We present newly obtained three-dimensional gaseous maps of the Milky Way Galaxy; HI, H$_2$ and total-gas (HI plus H$_2$) maps, which were derived from the HI and $^{12}$CO($J=1$--0) survey data and rotation curves based on the kinematic distance. The HI
Nakanishi, Hiroyuki, Sofue, Yoshiaki
core   +1 more source

Spintronic Bayesian Hardware Driven by Stochastic Magnetic Domain Wall Dynamics

Advanced Science, EarlyView.
Magnetic Probabilistic Computing (MPC) utilizes intrinsic stochastic dynamics in domain walls to establish a hardware foundation for uncertainty‐aware artificial intelligence. Thermally driven domain‐wall fluctuations, voltage‐controlled magnetic anisotropy, and TMR readout enable fully electrical, tunable probabilistic inference.
Tianyi Wang, Bingqian Dai, Shijie Xu, Kin Wong, Yaochen Li, Yang Cheng, Qingyuan Shu, Haoran He, Puyang Huang, Hanshen Huang, Xixiang Zhang, Kang L. Wang   +11 more
wiley   +1 more source

Flexible Dual-Band Ultrathin Frequency Selective Surface With Polarization Independence, Angular Stability, and Bending Insensitivity

IEEE Access
This paper introduces a novel ultrathin frequency selective surface (FSS) based on interconnected logarithmic spiral geometries. The structure is fabricated on a flexible polyimide substrate with a thickness of 0.05 mm, a relative permittivity of 4.3 ...
Maciel Alves de Oliveira, Ruann Victor de Andrade Lira, Alfredo Gomes Neto, Juliete da Silva Souza, Antonio Luiz Pereira de Siqueira Campos, Alexandre Jean Rene Serres   +5 more
doaj   +1 more source

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

Remarkable curves as images of circles and lines under conformal maps

Дифференциальная геометрия многообразий фигур, 2018
We consider images of a family of circles under some conformal maps. It is shown that the images of these lines are remarkable curves, such as cardioid, lemniscate of Bernoulli, logarithmic spiral.
A. Kochina
doaj